Improvement of Two-Stage Centrifugal Blood Pump for Cardiopulmonary Support System and Evaluation of Anti-Hemolysis Performance

Horiguchi, Hironori; Tsukiya, Tomonori; Takemika, Toratarou; Nomoto, Takeshi; Tsujimoto, Yoshinobu

doi:http://dx.doi.org/10.5293/IJFMS.2015.8.1.001

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자료유형: 학술저널

저자정보: Horiguchi, Hironori Tsukiya, Tomonori Takemika, Toratarou Nomoto, Takeshi Tsujimoto, Yoshinobu

저널정보: 한국유체기계학회 International Journal of Fluid Machinery and Systems International Journal of Fluid Machinery and Systems Vol.8 No.1

발행연도: 2015.3

수록면: 1 - 12 (12page)

DOI: http://dx.doi.org/10.5293/IJFMS.2015.8.1.001

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In cardiopulmonary support systems with a membrane oxygenation such as a percutaneous cardiopulmonary support (PCPS) or an extracorporeal membrane oxygenation (ECMO), blood pumps need to generate the pressure rise of approximately 200mmHg or higher, due to the high hydraulic resistances of the membrane oxygenation and of the cannula tubing. In order to realize the blood pump with higher pressure rise, higher anti-hemolysis and thrombosis performances, the development of novel centrifugal blood pump composed of two-stage has been conducted by the authors. In the present paper, effective attempts to decrease the wall shear stress and to suppress the stagnation are introduced for the prevention of hemolysis and thrombosis in blood pumps. The hemolysis test was also carried out and it was clarified that the decrease of wall shear stress is effective as a guideline of design of blood pumps for improving the anti-hemolysis performance.

#Blood #Hemolysis #Thrombosis #Artificial Heart #Centrifugal Pump

참고문헌 (8)

참고문헌 신청

Hironori Horiguchi / 2014 / Study on the Development of Two-Stage Centrifugal Blood Pump for Cardiopulmonary Support System / International Journal of Fluid Machinery and Systems 7(4):142~150

ANSYS, Inc. / 2006 / ANSYS CFX-Solver Modeling Guide / Release :125~127

ANSYS, Inc. / 2006 / ANSYS CFX-Solver Theory Guide / ANSYS CFX-Solver Theory Guide, Release :110~111

Takeda, H. / 2005 / Basic Design on Pumps (in Japanese) / Dengyosha Technical Review 29(2):7~14

Kameneva, M. V. / 2004 / Effects of Turbulent Stresses upon Mechanical Hemolysis: Experimental and Computational Analysis / ASAIO Journal 50(5):418~423

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