지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.3
- 수록면
- 35 - 41 (7page)
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초록· 키워드
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Background: Ambient air pollution has a negative effect on many diseases, such as cardiovascular and respiratory diseases. Recent studies have reported a relationship between air pollution and renal function, but the results were limited to exposure to particulate matter (PM). This study was to identify associations between various air pollutants and renal function among Korean adults.
Methods: Nationwide survey data for a total of 24,407 adults were analyzed. We calculated the estimated glomerular filtration rate (eGFR) for each individual to assess their renal function and used this to categorize those with chronic kidney disease (CKD). To evaluate exposure to ambient air pollution, we used the annual mean concentrations of four ambient air pollutants: PM with an aerodynamic diameter ≤ 10 μm (PM<SUB>10</SUB>), nitrogen dioxide (NO₂), sulfur dioxide (SO₂), and carbon monoxide (CO).
Results: We identified significant inverse relationships between the air pollutants PM<SUB>10</SUB> and NO₂ and eGFR in all statistical adjustment models (all p < 0.05). In the full covariate model, interquartile range increases in the annual mean concentrations of PM<SUB>10</SUB> and NO₂ were associated with decreases in eGFR levels of 0.46 (95% CI = . 0.87, . 0.04) and 0. 85 (95% CI = . 1.40, . 0.30), respectively. Three of the ambient air pollutants were significantly related to an increased risk of CKD in the unadjusted model (p < 0.0001), but all significant associations disappeared after adjusting for covariates (all p> 0.05).
Conclusions: Exposures to PM<SUB>10</SUB> and NO₂ were significantly associated with decreases in eGFR levels, but not CKD, in Korean adults.
Methods: Nationwide survey data for a total of 24,407 adults were analyzed. We calculated the estimated glomerular filtration rate (eGFR) for each individual to assess their renal function and used this to categorize those with chronic kidney disease (CKD). To evaluate exposure to ambient air pollution, we used the annual mean concentrations of four ambient air pollutants: PM with an aerodynamic diameter ≤ 10 μm (PM<SUB>10</SUB>), nitrogen dioxide (NO₂), sulfur dioxide (SO₂), and carbon monoxide (CO).
Results: We identified significant inverse relationships between the air pollutants PM<SUB>10</SUB> and NO₂ and eGFR in all statistical adjustment models (all p < 0.05). In the full covariate model, interquartile range increases in the annual mean concentrations of PM<SUB>10</SUB> and NO₂ were associated with decreases in eGFR levels of 0.46 (95% CI = . 0.87, . 0.04) and 0. 85 (95% CI = . 1.40, . 0.30), respectively. Three of the ambient air pollutants were significantly related to an increased risk of CKD in the unadjusted model (p < 0.0001), but all significant associations disappeared after adjusting for covariates (all p> 0.05).
Conclusions: Exposures to PM<SUB>10</SUB> and NO₂ were significantly associated with decreases in eGFR levels, but not CKD, in Korean adults.
목차
Abstract
Background
Methods
Results
Discussion
Conclusions
References
참고문헌 (23)
참고문헌 신청
Brook RD / 2010 / Particulate matter air pollution and cardiovascular disease : an update to the scientific statement from the American Heart Association / Circulation 121:2331~2378
Farhat SC / 2011 / Air pollution in autoimmune rheumatic diseases : a review / Autoimmun Rev 11:14~21
Hoek G / 2013 / Longterm air pollution exposure and cardio-respiratory mortality : a review / Environ Health 12:43
Sunyer J / 2001 / Urban air pollution and chronic obstructive pulmonary disease : a review / Eur Respir J 17:1024~1033
Liu YS / 2015 / Association between air pollutants and cardiovascular disease mortality in Wuhan, China / Int J Env Res Pub He 12:3506~3516
Farhat SC / 2011 / Air pollution in autoimmune rheumatic diseases : a review / Autoimmun Rev 11:14~21
Hoek G / 2013 / Longterm air pollution exposure and cardio-respiratory mortality : a review / Environ Health 12:43
Sunyer J / 2001 / Urban air pollution and chronic obstructive pulmonary disease : a review / Eur Respir J 17:1024~1033
Liu YS / 2015 / Association between air pollutants and cardiovascular disease mortality in Wuhan, China / Int J Env Res Pub He 12:3506~3516
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