지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.94 No.1
- 발행연도
- 2018.1
- 수록면
- 1 - 7 (7page)
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초록· 키워드
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Purpose: The purpose of this study was to evaluate the efficacy of Betafoam in terms of wound healing and safety.
Methods: Fifty-four male adult Sprague-Dawley rats (weight, 200–250 g) were used in the study. Full-thickness skin defects were created on the back of each rats. The rats were assigned to 6 groups according to the type of wound dressing used (n = 9 for each group): Betafoam, Allevyn-Ag, Mepilex-Ag, Medifoam silver, Polymem-Ag, and gauze. The wound size, histological findings, and amount of DNA on the changed dressings for each group were analyzed and compared.
Results: All groups showed an effective decrease in wound size. However, the differences between Betafoam and the other dressings were statistically significant on day 14 (P < 0.05). The number of newly generated blood vessels in the Betafoam group was significantly higher than in the gauze, Allevyn-Ag, and Medifoam silver groups (P < 0.001). In the Betafoam group, the proportion of collagen deposition was highest and showed a significantly superior arrangement of collagen fibers compared with the gauze, Allevyn-Ag, Mepilex-Ag, and Medifoam silver groups. The total content of the remaining DNA counts of the exchanged dressings were significantly lower in the Betafoam group than the others.
Conclusion: Betafoam is effective in wound healing and provides the best performance amongst the various types of dressing materials in terms of re-epithelialization, angiogenesis, collagen deposition, and tissue invasion.
Methods: Fifty-four male adult Sprague-Dawley rats (weight, 200–250 g) were used in the study. Full-thickness skin defects were created on the back of each rats. The rats were assigned to 6 groups according to the type of wound dressing used (n = 9 for each group): Betafoam, Allevyn-Ag, Mepilex-Ag, Medifoam silver, Polymem-Ag, and gauze. The wound size, histological findings, and amount of DNA on the changed dressings for each group were analyzed and compared.
Results: All groups showed an effective decrease in wound size. However, the differences between Betafoam and the other dressings were statistically significant on day 14 (P < 0.05). The number of newly generated blood vessels in the Betafoam group was significantly higher than in the gauze, Allevyn-Ag, and Medifoam silver groups (P < 0.001). In the Betafoam group, the proportion of collagen deposition was highest and showed a significantly superior arrangement of collagen fibers compared with the gauze, Allevyn-Ag, Mepilex-Ag, and Medifoam silver groups. The total content of the remaining DNA counts of the exchanged dressings were significantly lower in the Betafoam group than the others.
Conclusion: Betafoam is effective in wound healing and provides the best performance amongst the various types of dressing materials in terms of re-epithelialization, angiogenesis, collagen deposition, and tissue invasion.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (14)
참고문헌 신청
[학술지(정기간행물)] - Yuksel EB / 2014 / The effect of different topical agents (silver sulfadiazine, povidone-iodine, and sodium chloride 0.9%) on burn injuries in rats / Plast Surg Int 2014
[학술지(정기간행물)] - Prestes MA / 2012 / Wound healing using ionic silver dressing and nanocrystalline silver dressing in rats / Acta Cir Bras 27 : 761 ~ 767
[학술지(정기간행물)] - Lin YH / 2012 / Evaluation of silver-containing activated carbon fiber for wound healing study: In vitro and in vivo / J Biomed Mater Res B Appl Biomater 100 : 2288 ~ 2296
[학술지(정기간행물)] - Abdelrahman T / 2011 / Wound dressings: principles and practice / Surgery (Oxford) 29 : 491 ~ 495
[학술지(정기간행물)] - Lee JH / 2013 / Comparative efficacy of silver-containing dressing materials for treating MRSA-infected wounds in rats with streptozotocin-induced diabetes / Wounds 25 : 345 ~ 354
[학술지(정기간행물)] - Prestes MA / 2012 / Wound healing using ionic silver dressing and nanocrystalline silver dressing in rats / Acta Cir Bras 27 : 761 ~ 767
[학술지(정기간행물)] - Lin YH / 2012 / Evaluation of silver-containing activated carbon fiber for wound healing study: In vitro and in vivo / J Biomed Mater Res B Appl Biomater 100 : 2288 ~ 2296
[학술지(정기간행물)] - Abdelrahman T / 2011 / Wound dressings: principles and practice / Surgery (Oxford) 29 : 491 ~ 495
[학술지(정기간행물)] - Lee JH / 2013 / Comparative efficacy of silver-containing dressing materials for treating MRSA-infected wounds in rats with streptozotocin-induced diabetes / Wounds 25 : 345 ~ 354
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UCI(KEPA) : I410-ECN-0101-2018-514-001683776