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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 828 - 840 (13page)
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초록· 키워드
오류제보하기
In recent years, many researchers and clinicians found interest in regenerative medicine using induced pluripotent stem cells (iPSCs) with biomaterials due to their pluripotency, which is able to differentiate into any type of cells without human embryo, which of use is ethically controversial. However, there are limitations to make iPSCs from adult somatic cells due to their low stemness and donor site morbidity. Recently, to overcome above drawbacks, dental tissue-derived iPSCs have been highlighted as a type of alternative sources for their high stemness, easy gathering, and their complex (ectomesenchymal) origin, which easily differentiate them to various cell types for nerve, vessel, and other dental tissue regeneration. In other part, utilizing biomaterials for regenerative medicine using cell is recently highlighted because they can modulate cell adhesion, proliferation and (de)differentiation. Therefore, this paper will convey the overview of advantages and drawbacks of dental tissue-derived iPSCs and their future application with biomaterials.
목차
ABSTRACT
Ⅰ. 서론
Ⅱ. 유도만능줄기세포 역사 및 생체재료를 이용한 리프로그래밍
Ⅲ. 구강조직유래 유도만능줄기세포의 장점
Ⅳ. 구강조직유래 유도만능줄기세포의 단점 및 개선노력
Ⅴ. 구강조직유래 유도만능줄기세포-생체재료 복합체의 바이오 메디칼 적용
Ⅵ. 결론
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UCI(KEPA) : I410-ECN-0101-2018-515-001537154