지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.93 No.5
- 발행연도
- 2017.11
- 수록면
- 260 - 265 (6page)
이용수
초록· 키워드
오류제보하기
Purpose: The mechanism by which bariatric surgery facilitates diabetic control is still unknown. Duodenojejunal bypass supports the foregut theory; however, its efficacy when used alone is not yet established.
Methods: During the period from January 2008 to December 2009, patients who underwent laparoscopic duodenojejunal bypass (LDJB) or laparoscopic Roux-en-Y gastric bypass (LRYGB) for type 2 diabetes mellitus (T2DM) with or without morbid obesity were included. Patients who had a follow-up for less than 3 years were excluded. Patient baseline characteristics, change of body weight, body mass index (BMI), glycosylated hemoglobin (HbA1c), and diabetic treatments were analyzed.
Results: In total, 8 LDJB and 20 LRYGB patients were analyzed. The LDJB group had more number of male patients than the LRYGB group (LDJB 75% vs. LRYGB 30%, P = 0.030). Baseline BMI in the LRYGB group was higher than in the LDJB group (LDJB 27.0 ± 2.5 vs. LRYGB 32.6 ± 3.4, P < 0.001). Age, DM duration, baseline HbA1c, and C-peptide levels were similar. Longer operation time was needed to perform LDJB (LDJB 367.5 ± 120.2 vs. LRYGB 232.9 ± 41.1, P < 0.001), but no differences were observed in the hospital stay and complication rate between the 2 groups. At the third year of follow-up, the T2DM remission rate was observed in 40% of patients in the LRYGB group and 12.5% of patients in the LDJB group.
Conclusion: LDJB is not an effective method for controlling T2DM compared with LRYGB. Foregut theory may not be the main mechanism of diabetic control during bariatric surgery.
Methods: During the period from January 2008 to December 2009, patients who underwent laparoscopic duodenojejunal bypass (LDJB) or laparoscopic Roux-en-Y gastric bypass (LRYGB) for type 2 diabetes mellitus (T2DM) with or without morbid obesity were included. Patients who had a follow-up for less than 3 years were excluded. Patient baseline characteristics, change of body weight, body mass index (BMI), glycosylated hemoglobin (HbA1c), and diabetic treatments were analyzed.
Results: In total, 8 LDJB and 20 LRYGB patients were analyzed. The LDJB group had more number of male patients than the LRYGB group (LDJB 75% vs. LRYGB 30%, P = 0.030). Baseline BMI in the LRYGB group was higher than in the LDJB group (LDJB 27.0 ± 2.5 vs. LRYGB 32.6 ± 3.4, P < 0.001). Age, DM duration, baseline HbA1c, and C-peptide levels were similar. Longer operation time was needed to perform LDJB (LDJB 367.5 ± 120.2 vs. LRYGB 232.9 ± 41.1, P < 0.001), but no differences were observed in the hospital stay and complication rate between the 2 groups. At the third year of follow-up, the T2DM remission rate was observed in 40% of patients in the LRYGB group and 12.5% of patients in the LDJB group.
Conclusion: LDJB is not an effective method for controlling T2DM compared with LRYGB. Foregut theory may not be the main mechanism of diabetic control during bariatric surgery.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (18)
참고문헌 신청
[학술지(정기간행물)] - 허윤석 / 2013 / The effect of duodenojejunal bypass for type 2 diabetes mellitus patients below body mass index 25 kg/m2: one year follow-up / 대한외과학회지 85 (3) : 109 ~ 115
[학술지(정기간행물)] - Wild S / 2004 / Global prevalence of diabetes : estimates for the year 2000 and projections for 2030 / Diabetes Care 27 : 1047 ~ 1053
[학술지(정기간행물)] - Ntuk UE / 2014 / Ethnic-specific obesity cutoffs for diabetes risk : cross-sectional study of 490, 288 UK biobank participants / Diabetes Care 37 : 2500 ~ 2507
[학술지(정기간행물)] - Lee HJ / 2016 / Nationwide survey on bariatric and metabolic surgery in Korea : 2003-2013 Results / Obes Surg 26 : 691 ~ 695
[학술지(정기간행물)] - Ji Yeon Park / 2015 / Laparoscopic sleeve gastrectomy in obese Korean patients: up to 4-year follow-up in a single center / 대한외과학회지 88 (5) : 246 ~ 252
[학술지(정기간행물)] - Wild S / 2004 / Global prevalence of diabetes : estimates for the year 2000 and projections for 2030 / Diabetes Care 27 : 1047 ~ 1053
[학술지(정기간행물)] - Ntuk UE / 2014 / Ethnic-specific obesity cutoffs for diabetes risk : cross-sectional study of 490, 288 UK biobank participants / Diabetes Care 37 : 2500 ~ 2507
[학술지(정기간행물)] - Lee HJ / 2016 / Nationwide survey on bariatric and metabolic surgery in Korea : 2003-2013 Results / Obes Surg 26 : 691 ~ 695
[학술지(정기간행물)] - Ji Yeon Park / 2015 / Laparoscopic sleeve gastrectomy in obese Korean patients: up to 4-year follow-up in a single center / 대한외과학회지 88 (5) : 246 ~ 252
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UCI(KEPA) : I410-ECN-0101-2018-514-001438091