지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.92 No.6
- 발행연도
- 2017.6
- 수록면
- 411 - 418 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: The pathways of lymphatic metastases differ according to the tumor location in pancreatic cancer patients. However, it is unclear whether extended lymph node dissection (LND) is essential for all left-sided pancreatic cancer. The aim of this study is to evaluate the survival outcomes according to the extent of LND and tumor location in patients with left-sided pancreatic cancer.
Methods: January 2005 to December 2013, we retrospectively identified 107 patients who underwent curative intent surgery for left-sided pancreatic cancer. The left-sided pancreatic cancer was defined as a tumor located in pancreatic body or tail. The extent of LND was divided into 2 groups: extended LND and peripancreatic LND. The extended LND group included celiac and superior mesenteric LNs.
Results: We included 107 patients with left-sided pancreatic cancer; 59 patients with pancreatic body cancer and 48 patients with pancreatic tail cancer. The median follow-up period was 17 months (range, 3–110 months). Fifty patients with pancreatic body cancer and 30 patients with pancreatic tail cancer underwent extended LND. In patients with pancreatic body cancer, extended LND was associated with improved disease-free survival (DFS) (P = 0.010) and overall survival (P = 0.014). However, extended LND was not associated with DFS in patients with pancreatic tail cancer.
Conclusion: Extended LND could improve survival in patients with pancreatic body cancer. However, extended LND had no survival benefit for the treatment of pancreatic tail cancer.
Methods: January 2005 to December 2013, we retrospectively identified 107 patients who underwent curative intent surgery for left-sided pancreatic cancer. The left-sided pancreatic cancer was defined as a tumor located in pancreatic body or tail. The extent of LND was divided into 2 groups: extended LND and peripancreatic LND. The extended LND group included celiac and superior mesenteric LNs.
Results: We included 107 patients with left-sided pancreatic cancer; 59 patients with pancreatic body cancer and 48 patients with pancreatic tail cancer. The median follow-up period was 17 months (range, 3–110 months). Fifty patients with pancreatic body cancer and 30 patients with pancreatic tail cancer underwent extended LND. In patients with pancreatic body cancer, extended LND was associated with improved disease-free survival (DFS) (P = 0.010) and overall survival (P = 0.014). However, extended LND was not associated with DFS in patients with pancreatic tail cancer.
Conclusion: Extended LND could improve survival in patients with pancreatic body cancer. However, extended LND had no survival benefit for the treatment of pancreatic tail cancer.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (24)
참고문헌 신청
[학술지(정기간행물)] - Strasberg SM / 2003 / Radical antegrade modular pancreatosplenectomy / Surgery 133 : 521 ~ 527
[학술지(정기간행물)] - Strasberg SM / 2007 / Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas : ability to obtain negative tangential margins / J Am Coll Surg 204 : 244 ~ 249
[학술지(정기간행물)] - Chang YR / 2012 / Surgical outcome of pancreatic cancer using radical antegrade modular pancreatosplenectomy procedure / World J Gastroenterol 18 : 5595 ~ 5600
[학술지(정기간행물)] - Park HJ / 2014 / Role of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas / World J Surg 38 : 186 ~ 193
[학술지(정기간행물)] - Mitchem JB / 2012 / Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure / J Am Coll Surg 214 : 46 ~ 52
[학술지(정기간행물)] - Strasberg SM / 2007 / Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas : ability to obtain negative tangential margins / J Am Coll Surg 204 : 244 ~ 249
[학술지(정기간행물)] - Chang YR / 2012 / Surgical outcome of pancreatic cancer using radical antegrade modular pancreatosplenectomy procedure / World J Gastroenterol 18 : 5595 ~ 5600
[학술지(정기간행물)] - Park HJ / 2014 / Role of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas / World J Surg 38 : 186 ~ 193
[학술지(정기간행물)] - Mitchem JB / 2012 / Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure / J Am Coll Surg 214 : 46 ~ 52
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UCI(KEPA) : I410-ECN-0101-2018-514-000894968