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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 246 - 255 (10page)
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Co-production of 3-hydroxypropionic acid (3-HP) and 1,3-propanediol (1,3-PDO) was suggested as an innovative strategy to overcome several limitations occurring in the single production of 3-HP from glycerol. In this study, two new isolates of Klebsiella pneumoniae, which produce less lipopolysaccharide (LPS) thus considered less pathogenic than K. pneumoniae DSM 2026, were compared and evaluated for their potential for the co-production of 3-HP and 1,3-PDO. The newly isolated strains showed significantly faster sedimentation rate than DSM, which should be beneficial for downstream processing. Analysis of genome sequences of the isolates confirmed the presence of all genes necessary for glycerol assimilation, 1,3-PDO production and biosynthesis of coenzyme B12. Co-production yield was highest under anaerobic condition while cell growth was highest under aerobic condition. Both strains showed similarly good performance for the co-production although J2B gave the slightly higher co-production yield of 0.80 mol/mol than GSC021 (0.75 mol/mol). The evaluation of the newly developed strains presented here should be useful in designing similar evaluation experiments for other microorganisms.
목차
Abstract
1. INTRODUCTION
2. MATERIALS AND METHODS
3. RESULTS AND DISCUSSION
4. CONCLUSION
REFERENCES
참고문헌 (23)
참고문헌 신청
[인터넷자원] - / / Cover story (Catalyst) - Future chemical industry
[학술지(정기간행물)] - Bozell, J. J. / 2010 / Technology development for the production of biobased products from biorefinery carbohydrates - the US Department of Energy’s “top 10” revisited / Green Chem 12 : 539 ~ 554
[학술지(정기간행물)] - Kumar, V. / 2013 / Recent advances in biological production of 3-hydroxypropionic acid / Biotechnol. Adv 31 : 945 ~ 961
[학술지(정기간행물)] - Raj, S. M. / 2008 / Production of 3-hydroxypropionic acid from glycerol by a novel recombinant Escherichia coli BL21 strain / Process Biochem 43 : 1440 ~ 1446
[학술지(정기간행물)] - Rathnasingh, C. / 2009 / Development and evaluation of efficient recombinant Escherichia coli strains for the production of 3-hydroxypropionic acid from glycerol / Biotechnol. Bioeng 104 : 729 ~ 739
[학술지(정기간행물)] - Bozell, J. J. / 2010 / Technology development for the production of biobased products from biorefinery carbohydrates - the US Department of Energy’s “top 10” revisited / Green Chem 12 : 539 ~ 554
[학술지(정기간행물)] - Kumar, V. / 2013 / Recent advances in biological production of 3-hydroxypropionic acid / Biotechnol. Adv 31 : 945 ~ 961
[학술지(정기간행물)] - Raj, S. M. / 2008 / Production of 3-hydroxypropionic acid from glycerol by a novel recombinant Escherichia coli BL21 strain / Process Biochem 43 : 1440 ~ 1446
[학술지(정기간행물)] - Rathnasingh, C. / 2009 / Development and evaluation of efficient recombinant Escherichia coli strains for the production of 3-hydroxypropionic acid from glycerol / Biotechnol. Bioeng 104 : 729 ~ 739
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UCI(KEPA) : I410-ECN-0101-2017-470-001981596