지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.90 No.6
- 발행연도
- 2016.5
- 수록면
- 322 - 327 (6page)
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초록· 키워드
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Purpose: Thrombocytosis is known to be a poor prognostic factor in several types of solid tumors. The prognostic role of preoperative thrombocytosis in colorectal cancer remains limited. The aim of this study is to investigate the prognostic role of preoperative thrombocytosis in stage II colorectal cancer.
Methods: Two hundred eighty-four patients with stage II colorectal cancer who underwent surgical resection between December 2003 and December 2009 were retrospectively reviewed. Thrombocytosis was defined as platelet > 450 × 10<SUP>9</SUP>/L. We compared patients with thrombocytosis and those without thrombocytosis in terms of survival.
Results: The 5-year disease-free survival (DFS) rates were lower in patients with thrombocytosis compared to those without thrombocytosis in stage II colorectal cancer (73.3% vs. 89.6%, P = 0.021). Cox multivariate analysis demonstrated that thrombocytosis (hazard ratio, 2.945; 95% confidence interval, 1.127–7.697; P = 0.028) was independently associated with DFS in patients with stage II colorectal cancer.
Conclusion: This study showed that thrombocytosis is a prognostic factor predicting DFS in stage II colorectal cancer patients.
Methods: Two hundred eighty-four patients with stage II colorectal cancer who underwent surgical resection between December 2003 and December 2009 were retrospectively reviewed. Thrombocytosis was defined as platelet > 450 × 10<SUP>9</SUP>/L. We compared patients with thrombocytosis and those without thrombocytosis in terms of survival.
Results: The 5-year disease-free survival (DFS) rates were lower in patients with thrombocytosis compared to those without thrombocytosis in stage II colorectal cancer (73.3% vs. 89.6%, P = 0.021). Cox multivariate analysis demonstrated that thrombocytosis (hazard ratio, 2.945; 95% confidence interval, 1.127–7.697; P = 0.028) was independently associated with DFS in patients with stage II colorectal cancer.
Conclusion: This study showed that thrombocytosis is a prognostic factor predicting DFS in stage II colorectal cancer patients.
목차
INTRODUCTION
METHODS
RESUTLS
DISCUSSION
REFERENCES
참고문헌 (18)
참고문헌 신청
[학술지(정기간행물)] - O’Connell MJ. / 1997 / Controlled trial of fluorouracil and lowdose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer / J Clin Oncol 15 : 246 ~ 250
[학술지(정기간행물)] - Zaniboni A. / 2004 / Adjuvant therapy for stage II colon cancer : an elephant in the living room? / Ann Oncol 15 : 1310 ~ 1318
[학술지(정기간행물)] - Griffin MR. / 1987 / Predictors of survival after curative resection of carcinoma of the colon and rectum / Cancer 60 : 2318 ~ 2324
[학술지(정기간행물)] - Wiggers T. / 1988 / Regression analysis of prognostic factors in colorectal cancer after curative resections / Dis Colon Rectum 31 : 33 ~ 41
[학술지(정기간행물)] - Minsky BD. / 1989 / Lymphatic vessel invasion is an independent prognostic factor for survival in colorectal cancer / Int J Radiat Oncol Biol Phys 17 : 311 ~ 318
[학술지(정기간행물)] - Zaniboni A. / 2004 / Adjuvant therapy for stage II colon cancer : an elephant in the living room? / Ann Oncol 15 : 1310 ~ 1318
[학술지(정기간행물)] - Griffin MR. / 1987 / Predictors of survival after curative resection of carcinoma of the colon and rectum / Cancer 60 : 2318 ~ 2324
[학술지(정기간행물)] - Wiggers T. / 1988 / Regression analysis of prognostic factors in colorectal cancer after curative resections / Dis Colon Rectum 31 : 33 ~ 41
[학술지(정기간행물)] - Minsky BD. / 1989 / Lymphatic vessel invasion is an independent prognostic factor for survival in colorectal cancer / Int J Radiat Oncol Biol Phys 17 : 311 ~ 318
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UCI(KEPA) : I410-ECN-0101-2017-514-001019529