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논문 기본 정보

자료유형
학술대회자료
저자정보
Jin-Woo Lee (Inha University School of Medicine)
저널정보
한국간담췌외과학회 한국간담췌외과학회 학술대회지 한국간담췌외과학회 2014년 제40차 춘계학술대회
발행연도
2014.4
수록면
403 - 410 (8page)

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초록· 키워드

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Therapy for hepatitis C is undergoing a revolution. All-oral, interferon-free combinations of drugs are expected to cure more than 90% of infections. A huge amount of data from clinical trials are presented regularly at international conferences or released to the press, creating confusion in the viral hepatitis field. Even though new DAAs have stronger antiviral activity against HCV, there are still a lot of difficult-to-treat patients infected with HCV. Clinicians also need to be aware of drug-drug interaction as well as other adverse events with the use of most DAAs. Many unanswered questions remain, such as how to re-treat patients who failed on treatment, the potent role of interferon-free regimens, and how to best treat these special populations.
This review outlines best treatment strategies for difficult to treat HCV patients, including those that are interferon-based and interferon-free.

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HCV-infected patients who fail DAA therapies
HCV-infected patients with advanced fibrosis/cirrhosis
Elderly patients
HCV-HIV co-infected patients
HCV-infected patients associated with liver transplantation
HCV-infected patients with renal impairment or ESRD requiring hemodialysis
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