지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.90 No.3
- 발행연도
- 2016.2
- 수록면
- 124 - 130 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: Intraductal papillary mucinous neoplasm (IPMN) has variable malignant potential ranging from premalignant intraductal lesions to malignant neoplasms with invasive carcinoma. To help physicians managing patients with IPMN, International consensus guidelines was made in 2006 and revised in 2012. This study was designed to evaluate the clinical usefulness of guidelines and to validate.
Methods: From October 1996 to December 2011, we retrospectively reviewed the data of 230 patients who underwent pancreatic resection for IPMN. Univariate and multivariable analyses were used to identify significant predictors of malignancy in IPMN.
Results: Of the 230 patients, 62 patients (27%) were diagnosed with invasive carcinoma. Jaundice (P < 0.001; 95% confidence interval [CI], 3.086–40.010) main pancreatic duct diameter equal to or greater than 10 mm (P < 0.001; 95% CI, 1.723–6.673) and also abdominal pain (P < 0.001; 95% CI, 4.363–22.600) show statistical significance in univariate and multivariate analysis. “High-risk stigmata” was statistical powerful predictors of malignancy than “worrisome features”. International consensus guidelines 2012 had improvement on specificity but deterioration of sensitivity.
Conclusion: Revised guidelines seemed to bring about an improvement of weak side of Sendai criteria. Abdominal pain, jaundice, main pancreas duct greater than 10 mm can be clinical variables to predict malignancy.
Methods: From October 1996 to December 2011, we retrospectively reviewed the data of 230 patients who underwent pancreatic resection for IPMN. Univariate and multivariable analyses were used to identify significant predictors of malignancy in IPMN.
Results: Of the 230 patients, 62 patients (27%) were diagnosed with invasive carcinoma. Jaundice (P < 0.001; 95% confidence interval [CI], 3.086–40.010) main pancreatic duct diameter equal to or greater than 10 mm (P < 0.001; 95% CI, 1.723–6.673) and also abdominal pain (P < 0.001; 95% CI, 4.363–22.600) show statistical significance in univariate and multivariate analysis. “High-risk stigmata” was statistical powerful predictors of malignancy than “worrisome features”. International consensus guidelines 2012 had improvement on specificity but deterioration of sensitivity.
Conclusion: Revised guidelines seemed to bring about an improvement of weak side of Sendai criteria. Abdominal pain, jaundice, main pancreas duct greater than 10 mm can be clinical variables to predict malignancy.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (30)
참고문헌 신청
Fernandez-del Castillo C, Adsay NV. Intraductal papillary mucinous neoplasms of the pancreas. Gastroenterology 2010;139: 708-13, 713.e1-2.
Kimura W, Nagai H, Kuroda A, Muto T, Esaki Y. Analysis of small cystic lesions of the pancreas. Int J Pancreatol 1995;18:197- 206.
Fernandez-del Castillo C, Targarona J, Thayer SP, Rattner DW, Brugge WR, Warshaw AL. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg 2003;138:427-3.
Grutzmann R, Post S, Saeger HD, Niedergethmann M. Intraductal papillary mucinous neoplasia (IPMN) of the pancreas: its diagnosis, treatment, and prognosis. Dtsch Arztebl Int 2011;108:788-94.
Swartz MJ, Hsu CC, Pawlik TM, Winter J, Hruban RH, Guler M, et al. Adjuvant chemoradiotherapy after pancreatic resection for invasive carcinoma associated with intraductal papillary mucinous neoplasm of the pancreas. Int J Radiat Oncol Biol Phys 2010;76:839-44.
Kimura W, Nagai H, Kuroda A, Muto T, Esaki Y. Analysis of small cystic lesions of the pancreas. Int J Pancreatol 1995;18:197- 206.
Fernandez-del Castillo C, Targarona J, Thayer SP, Rattner DW, Brugge WR, Warshaw AL. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg 2003;138:427-3.
Grutzmann R, Post S, Saeger HD, Niedergethmann M. Intraductal papillary mucinous neoplasia (IPMN) of the pancreas: its diagnosis, treatment, and prognosis. Dtsch Arztebl Int 2011;108:788-94.
Swartz MJ, Hsu CC, Pawlik TM, Winter J, Hruban RH, Guler M, et al. Adjuvant chemoradiotherapy after pancreatic resection for invasive carcinoma associated with intraductal papillary mucinous neoplasm of the pancreas. Int J Radiat Oncol Biol Phys 2010;76:839-44.
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Validation of international consensus guidelines 2012 for the management of intraductal papillary mucinous neoplasm of the pancreas
한국간담췌외과학회 학술대회지
2015 .09
-
How to Decide the Surgery in Patients with Intraductal Papillary Mucinous Neoplasm of the Pancreas : Validation of Proposed Nomogram Predicting the Individual Risk of Malignancy
대한외과학회 학술대회 초록집
2018 .11
-
Prevalence, Diagnosis and Management of Pancreatic Cystic Neoplasms: Current Status and Future Directions
Gut and Liver
2015 .01
-
Factors Predictive of Malignancy Potency in Pure Branch Duct Intraductal Papillary Mucinous Neoplasm of the Pancreas without Mural Nodules
Gut and Liver
2018 .01
-
[Hepato-Biliary and Pancreas] Risk Factors of Invasive Mucinous Cystic Neoplasm of Pancreas and Its Prognosis
대한외과학회 학술대회 초록집
2021 .11
-
Impact of adjuvant therapy in patients with invasive intraductal papillary mucinous neoplasms of the pancreas: An international multicenter study
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
Risk factors of malignant mucinous cystic neoplasm of pancreas and its prognosis
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
A Large Extra-parenchymal Intraductal Papillary Mucinous Neoplasm of Pancreas: A Case Report
대한외과학회 학술대회 초록집
2021 .11
-
Development of a Nomogram Based on Radiologic Findings for Predicting Malignancy and Invasiveness in Intraductal Papillary Mucinous Neoplasms of the Pancreas: An International Multicenter Study
대한외과학회 학술대회 초록집
2019 .10
-
Squamous cell carcinoma of the pancreas with a pancreatic intraductal papillary mucinous neoplasm: a case report
고신대학교 의과대학 학술지
2024 .03
-
Prediction of malignancy in main-duct intraductal papillary mucinous neoplasm (MD-IPMN) based on radiologic features: How should we treat if main duct dilatation is under 10 mm?
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
고위험 인자 또는 우려 인자를 가진 췌관 내 유두상 점액성 종양: 내과의사의 입장
대한췌담도학회지
2023 .01
-
Branch duct intraductal papillary mucinous neoplasm of the pancreas : single-center experience with 324 patients who underwent surgical resection
Annals of Hepato-Biliary-Pancreatic Surgery
2015 .08
-
Misty role of postoperative adjuvant therapy in resected invasive intraductal papillary mucinous neoplasm of the pancreas: A multicenter external validation
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Flat Type of Intraductal Papillary Mucinous Neoplasm of the Pancreas Differs from Papillary or Tubular Types in Terms of the Expression of Oncogenic Protein and Survival Outcome : A Proposal of a New Classification
대한외과학회 학술대회 초록집
2015 .05
-
Metastatic adenocarcinoma of the pancreas presents as metastases to the axillary/supraclavicular region as the first sign of the disease
Annals of Hepato-Biliary-Pancreatic Surgery
2017 .11
-
Mucinous Non-neoplastic cyst of Pancreas
대한외과학회 학술대회 초록집
2017 .11
-
Subtype of intraductal papillary mucinous neoplasm of the pancreas is important to the development of metachronous high-risk lesions after pancreatectomy
Annals of Hepato-Biliary-Pancreatic Surgery
2019 .11
-
Mucinous cystic neoplasm of Liver
대한외과학회 학술대회 초록집
2019 .10
-
Pancreas cancer
대한외과학회 학술대회 초록집
2015 .11
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Identification of Protein Arginine Methyltransferase 5 as a Regulator for Encystation of Acanthamoeba
Eun-Kyung Moon
,
Yeonchul Hong
,
Dong-Il Chung
외 2명
Parasites, Hosts and Diseases
2016
.04
Application of Diagnostic Microarray Technique in Subtyping and Pathotyping of Avian Influenza Viruses Isolated in Mongolia
Jung-Hoon Kwon
,
Ji-Hoon Kim
,
Dong-hun Lee
외 15명
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016
.03
Implications of Calcineurin/NFAT Inhibitors" Regulation of Dendritic Cells and Innate Immune Cells in Islet Xenotransplantation
Yong-Hee Kim
,
Won-Woo Lee
,
Chung-Gyu Pa
외 1명
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016
.03
Effects of Pregabalin in Primary Burning Mouth Syndrome Patients Unresponsive to Topical Clonazepam Treatment : A Retrospective Pilot Study
Jun-Young Heo
,
Jae-Woo Jeon
,
Soo-Min Ok
외 2명
Journal of Oral Medicine and Pain
2016
.03
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2016-514-002640555