지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: To establish scientific and objective evidence for the use of a Korean medicine, articles regarding Hwangryeonhaedok-tang (HRHDT), a herbal medicine frequently used in Korean medical clinics and hospitals, were gathered and analyzed.
Methods: The articles were classified as being from domestic or international journals, and by their year of publication. The mechanisms of the anti-inflammatory and antipyretic effects of HRHDT were investigated.
Results: Of the 25 articles analyzed, 7 were published from Korea, 7 were from China, and 11 were from Japan. HRHDT showed anti-inflammatory and antipyretic effects through the regulation of the expression of Th1 cytokines including interleukin-2 (IL-2), IL-8, interferon-γ (IFN-γ), and tumor necrosis factor-α (TNF-α); and Th2 cytokines including IL-4, IL-6, and IL-12, which inhibit leukotriene B4 (LTB4), cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE2), and inflammatory cells. It also lowered preprodynorphin (PPD), and corticotropin-releasing factor (CRF) in the peripheral nerve system and hypothalamus.
Conclusions: We speculate that the anti-inflammatory and antipyretic effects could be related to the therapeutic efficacy of HRHDT in removing pathogenic fire and heat.
Methods: The articles were classified as being from domestic or international journals, and by their year of publication. The mechanisms of the anti-inflammatory and antipyretic effects of HRHDT were investigated.
Results: Of the 25 articles analyzed, 7 were published from Korea, 7 were from China, and 11 were from Japan. HRHDT showed anti-inflammatory and antipyretic effects through the regulation of the expression of Th1 cytokines including interleukin-2 (IL-2), IL-8, interferon-γ (IFN-γ), and tumor necrosis factor-α (TNF-α); and Th2 cytokines including IL-4, IL-6, and IL-12, which inhibit leukotriene B4 (LTB4), cyclooxygenase-2 (COX-2), prostaglandin E2 (PGE2), and inflammatory cells. It also lowered preprodynorphin (PPD), and corticotropin-releasing factor (CRF) in the peripheral nerve system and hypothalamus.
Conclusions: We speculate that the anti-inflammatory and antipyretic effects could be related to the therapeutic efficacy of HRHDT in removing pathogenic fire and heat.
목차
Introduction
Materials and Methods
Results
Discussion
Conclusions
References
참고문헌 (53)
참고문헌 신청
1. [학술지(정기간행물)] - Yoshida H / 2010 / Mediates the Extra-Intestinal Thrombosis Associated with Experimental Colitis / Am J Pathol 177 (6) : 2774 ~ 2781
2. [학술지(정기간행물)] - Hoyer KK / 2008 / Interleukin-2 in the development and control of inflammatory disease / Immunol Rev 226 : 19 ~ 28
3. [학술지(정기간행물)] - Meier-Trummer CS / 2009 / Malignant catarrhal fever of cattle is associated with low abundance of IL-2 transcript and a predominantly latent profile of ovine herpesvirus 2 gene expression / Plos one 4 (7) : 1 ~ 12
4. [학술지(정기간행물)] - Cardoso CR / 2009 / IL-4 regulates susceptibility to intestinal inflammation in murine food allergy / Am J Physiol Gastrointest Liver Physiol 296 : 593 ~ 600
5. [학술지(정기간행물)] - Sehra S / 2008 / IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6 / J Immunol 180 : 3551 ~ 3559
2. [학술지(정기간행물)] - Hoyer KK / 2008 / Interleukin-2 in the development and control of inflammatory disease / Immunol Rev 226 : 19 ~ 28
3. [학술지(정기간행물)] - Meier-Trummer CS / 2009 / Malignant catarrhal fever of cattle is associated with low abundance of IL-2 transcript and a predominantly latent profile of ovine herpesvirus 2 gene expression / Plos one 4 (7) : 1 ~ 12
4. [학술지(정기간행물)] - Cardoso CR / 2009 / IL-4 regulates susceptibility to intestinal inflammation in murine food allergy / Am J Physiol Gastrointest Liver Physiol 296 : 593 ~ 600
5. [학술지(정기간행물)] - Sehra S / 2008 / IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6 / J Immunol 180 : 3551 ~ 3559
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UCI(KEPA) : I410-ECN-0101-2016-519-002228958