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논문 기본 정보

자료유형
학술저널
저자정보
Eun-Chae Yim (Chonnam National University) Hyeon Joe Kim (Chonnam National University) Seong-Jun Kim (Chonnam National University)
저널정보
환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Health and Toxicology 제29권
발행연도
2014.12
수록면
145 - 152 (8page)

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초록· 키워드

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Objectives : This study focused on the assessment of acute toxicity caused by Osthol, a major component of environment-friendly biological pesticides, by using two aquatic organisms.
Methods : The assessment of acute toxicity caused by Osthol was conducted in Daphnia magna and by examining the morphological abnormalities in Danio rerio embryos.
Results : The median effective concentration value of Osthol in D. magna 48 hours after inoculation was 19.3 μM. The median lethal concentration of D. rerio embryo at 96 hours was 30.6 μM. No observed effect concentration and predicted no effect concentration values of Osthol in D. magna and D. rerio were calculated as 5.4 and 0.19 μM, respectively. There was an increase in the morphological abnormalities in D. rerio embryo due to Osthol over time. Coagulation, delayed hatching, yolk sac edema, pericardial edema, and pigmentation were observed in embryos at 24–48 hours. Symptoms of scoliosis and head edema occurred after 72 hours. In addition, bent tails, ocular defects, and symptoms of collapse were observed in fertilized embryo tissue within 96 hours. Ocular defects and pigmentation were the additional symptoms observed in this study.
Conclusions : Because Osthol showed considerable toxicity levels continuous toxicity evaluation in agro-ecosystems is necessary when bio-pesticides containing Osthol are used.

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Introduction
Materials and Methods
Results
Discussion
References

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UCI(KEPA) : I410-ECN-0101-2016-539-002083244