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논문 기본 정보

자료유형
학술저널
저자정보
Soyoung Hong (Seoul Medical Center) Ho-Jang Kwon (Dankook University College of Medicine) Won-Jun Choi (Gachon University Gil Medical Center) Wan Ryung Lim (Seoul Medical Center) Jeonghoon Kim (Seoul Medical Center) KyooSang Kim (Seoul Medical Center)
저널정보
환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Health and Toxicology 제29권
발행연도
2014.12
수록면
120 - 125 (6page)

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Objectives : Antimicrobial chemicals are used in a variety of household and personal care products. Exposure to antimicrobial household products has been hypothesized to lead to allergic diseases in children.
Methods : We investigated antimicrobial household product exposure and allergic symptoms in Korean children. An antimicrobial exposure (AE) score was derived. To examine the symptoms of allergic diseases (current wheeze, current rhinitis, and current eczema) in the past 12 months, we used a questionnaire based on the core module of the International Study of Asthma and Allergies in Children. Complete data for the analysis were available for 25,805 of the 35,590 (72.5%) children.
Results : The prevalence of current allergic diseases was as follows: wheeze, 5.6%; allergic rhinitis, 32.6%; and eczema, 17.7%. The mean (standard deviation) AE score was 14.3 (9.3) (range: 0-40). Compared with subjects with a low AE score (reference), subjects with a high AE score (fourth quartile) were more likely to have symptoms of wheezing and allergic rhinitis (adjusted odds ratio [aOR] for wheezing 1.24, 95% confidence interval [CI], 1.05-1.45, p for trend=0.24; aOR for allergic rhinitis 1.30, 95% CI, 1.20-1.40, p <0.01).
Conclusions : These findings suggest that frequent use of antimicrobial household products was associated with current wheeze and current allergic rhinitis.

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Introduction
Materials and Methods
Results
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UCI(KEPA) : I410-ECN-0101-2016-539-002083219