지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.2
- 수록면
- 1 - 9 (9page)
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초록· 키워드
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Autophagy is a fundamental cellular process in eukaryotic cells for maintaining homeostasis by degrading cellular proteins and organelles. Recently, the roles of autophagy have been expanded to immune systems, which in turn modulate innate immune responses. More specifically, autophagy acts as a direct effector for protection against pathogens, as well as a modulator of pathogen recognition and downstream signaling in innate immune responses. In addition, autophagy controls autoimmunity and inflammatory disorders by negative regulation of immune signaling. In this review, we focus on recent advances in the role of autophagy in innate immune systems.
목차
INTRODUCTION
DIRECT ELIMINATION OF PATHOGENS BY AUTOPHAGY
INTERACTION BETWEEN AUTOPHAGY AND TOLL-LIKE RECEPTORS
AUTOPHAGY IN NUCLEOTIDE OLIGOMERIZATION DOMAIN-LIKE RECEPTOR SIGNALING
AUTOPHAGY IN ANTIVIRAL IMMUNITY
AUTOPHAGY IN REGULATION OF INFLAMMASOME
CONCLUSION
REFERENCES
참고문헌 (60)
참고문헌 신청
1. [학술지(정기간행물)] - Klionsky, D. J. / 2000 / Autophagy as a regulated pathway of cellular degradation / Science 290 : 1717 ~ 1721
2. [학술지(정기간행물)] - Mizushimam, N / 2007 / Protein turnover via autophagy: implications for metabolism / Annu. Rev. Nutr 27 : 19 ~ 40
3. [학술지(정기간행물)] - Massey, A. C. / 2006 / Chaperone- mediated autophagy in aging and disease / Curr. Top. Dev. Biol 73 : 205 ~ 235
4. [학술지(정기간행물)] - Cuervo, A. M. / 2000 / Unique properties of lamp2a compared to other lamp2 isoforms / J. Cell Sci 113 (Pt24) : 4441 ~ 4450
5. [학술지(정기간행물)] - Cuervo, A. M. / 1996 / A receptor for the selective uptake and degradation of proteins by lysosomes / Science 273 : 501 ~ 503
2. [학술지(정기간행물)] - Mizushimam, N / 2007 / Protein turnover via autophagy: implications for metabolism / Annu. Rev. Nutr 27 : 19 ~ 40
3. [학술지(정기간행물)] - Massey, A. C. / 2006 / Chaperone- mediated autophagy in aging and disease / Curr. Top. Dev. Biol 73 : 205 ~ 235
4. [학술지(정기간행물)] - Cuervo, A. M. / 2000 / Unique properties of lamp2a compared to other lamp2 isoforms / J. Cell Sci 113 (Pt24) : 4441 ~ 4450
5. [학술지(정기간행물)] - Cuervo, A. M. / 1996 / A receptor for the selective uptake and degradation of proteins by lysosomes / Science 273 : 501 ~ 503
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UCI(KEPA) : I410-ECN-0101-2016-511-001746179