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자료유형
학술저널
저자정보
Ralph A. Tripp (University of Georgia)
저널정보
대한면역학회 Immune Network Immune Network Vol.13 No.5
발행연도
2013.10
수록면
163 - 167 (5page)

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초록· 키워드

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The dynamics of the virus-host interface in the response to respiratory virus infection is not well-understood; however, it is at this juncture that host immunity to infection evolves. Respiratory viruses have been shown to modulate the host response to gain a replication advantage through a variety of mechanisms. Viruses are parasites and must co-opt host genes for replication, and must interface with host cellular machinery to achieve an optimal balance between viral and cellular gene expression. Host cells have numerous strategies to resist infection, replication and virus spread, and only recently are we beginning to understand the network and pathways affected. The following is a short review article covering some of the studies associated with the Tripp laboratory that have addressed how respiratory syncytial virus (RSV) operates at the virus-host interface to affects immune outcome and disease pathogenesis.

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INTRODUCTION
VIRUS-HOST INTERACTION
ROLE FOR RSV G PROTEIN IN MODULATING HOST RESPONSES
DEVELOPMENT OF DISEASE INTERVENTION STRATEGIES
FUTURE PERSPECTIVES
REFERENCES

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