지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.6
- 수록면
- 149 - 155 (7page)
이용수
초록· 키워드
오류제보하기
We performed this study to evaluate the role of Interleukin-17 (IL-17) and Interleukin-18 (IL-18) in insulin resistance during normal pregnancy. This descriptive cross sectional study was carried out on 97 healthy pregnant women including 32, 25, and 40 individuals in the first, second, and third trimesters, respectively, and on 28 healthy non pregnant women between the autumn of 2012 and the spring of 2013. We analyzed the serum concentrations of IL-17 and IL-18 by using the enzyme linked immunosorbent assay (ELISA). Insulin resistance was measured by homeostasis model assessment of insulin resistance equation. No significant differences between the demographic data of the pregnant and non pregnant groups were observed. Insulin resistant in pregnant women was significantly higher than the controls (p=0.006). Serum IL-17 concentration was significantly different in non pregnant women and pregnant women in all gestational ages (p<0.05). Serum IL-18 level was significantly lower in subjects with first, second, and third trimesters of pregnancy in compared to non pregnant women (p<0.05). No significant correlations were found between serum IL-17 and IL-18 levels with insulin resistance (r=0.08, p=0.34 vs. r=0.01, p=0.91, respectively). Our data suggested that IL-17 and IL-18 do not appear to attribute greatly to pregnancy deduced insulin resistance during normal pregnancy.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
1. [학술지(정기간행물)] - Hadden, D. R. / 2009 / Normal and abnormal maternal metabolism during pregnancy / Semin. Fetal Neonatal Med 14 : 66 ~ 71
2. [학술지(정기간행물)] - Baranyi, E. / 2011 / Diabetes and pregnancy / Orv Hetil 152 : 1635 ~ 1640
3. [학술지(정기간행물)] - Kirwan, J. P / 2002 / TNF-alpha is a predictor of insulin resistance in human pregnancy / Diabetes 51 : 2207 ~ 2213
4. [학술지(정기간행물)] - Gwozdziewiczova, S. / 2004 / Tumor necrosis factor alfa (TNFalpha) and insulin resistance / Cesk Fysiol 53 : 167 ~ 175
5. [학술지(정기간행물)] - Senn, J. J. / 2002 / Interleukin-6 induces cellular insulin resistance in hepatocytes / Diabetes 51 (12) : 3391 ~ 3399
2. [학술지(정기간행물)] - Baranyi, E. / 2011 / Diabetes and pregnancy / Orv Hetil 152 : 1635 ~ 1640
3. [학술지(정기간행물)] - Kirwan, J. P / 2002 / TNF-alpha is a predictor of insulin resistance in human pregnancy / Diabetes 51 : 2207 ~ 2213
4. [학술지(정기간행물)] - Gwozdziewiczova, S. / 2004 / Tumor necrosis factor alfa (TNFalpha) and insulin resistance / Cesk Fysiol 53 : 167 ~ 175
5. [학술지(정기간행물)] - Senn, J. J. / 2002 / Interleukin-6 induces cellular insulin resistance in hepatocytes / Diabetes 51 (12) : 3391 ~ 3399
이 논문의 저자 정보
최근 본 자료
댓글(0)
0