지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.4
- 수록면
- 95 - 99 (5page)
이용수
초록· 키워드
오류제보하기
Type 1 diabetes is one of the classical examples of organ-specific autoimmune diseases characterized by lymphocytic infiltration or inflammation in pancreatic islets called 'insulitis'. In contrast, type 2 diabetes has been traditionally regarded as a metabolic disorder with a pathogenesis that is totally different from that of type 1 diabetes. However, recent investigation has revealed contribution of chronic inflammation in the pathogenesis of type 2 diabetes. In addition to type 2 diabetes, the role of chronic inflammation is being appreciated in a wide variety of metabolic disorders such as obesity, metabolic syndrome, and atherosclerosis. In this review, we will cover the role of innate immunity in the pathogenesis of metabolic disorders with an emphasis on NLRP3.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
1. [학술지(정기간행물)] - Michelsen KS / 2004 / Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E / Proc Natl Acad Sci U S A 101 : 10679 ~ 10684
2. [학술지(정기간행물)] - Shi H / 2006 / TLR4 links innate immunity and fatty acid-induced insulin resistance / J Clin Invest 116 : 3015 ~ 3025
3. [학술지(정기간행물)] - Feuerer M / 2009 / Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters / Nat Med 15 : 930 ~ 939
4. [학술지(정기간행물)] - Hotamisligil GS / 1993 / Adipose expression of tumor necrosis factor-alpha: direct role in obesity- linked insulin resistance / Scien 259 : 87 ~ 91
5. [학술지(정기간행물)] - Kufer TA / 2011 / NLR functions beyond pathogen recognition / Nat Immunol 12 : 121 ~ 128
2. [학술지(정기간행물)] - Shi H / 2006 / TLR4 links innate immunity and fatty acid-induced insulin resistance / J Clin Invest 116 : 3015 ~ 3025
3. [학술지(정기간행물)] - Feuerer M / 2009 / Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters / Nat Med 15 : 930 ~ 939
4. [학술지(정기간행물)] - Hotamisligil GS / 1993 / Adipose expression of tumor necrosis factor-alpha: direct role in obesity- linked insulin resistance / Scien 259 : 87 ~ 91
5. [학술지(정기간행물)] - Kufer TA / 2011 / NLR functions beyond pathogen recognition / Nat Immunol 12 : 121 ~ 128
이 논문의 저자 정보
최근 본 자료
댓글(0)
0