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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.9
- 수록면
- 168 - 176 (9page)
이용수
초록· 키워드
오류제보하기
Vibrio vulnificus is a Gram-negative halophilic bacterium that causes necrotizing wound infections and fatal septicemia, which mainly occur in patients with elevated serum or tissue iron levels. Accumulated experimental data clearly show that V. vulnificus is a ferrophilic bacterium that requires more available iron for growth than other pathogenic bacteria, has multiple iron-uptake systems, which play important roles in the pathogenesis of the V. vulnificus infections. This review summarized the composition, regulation and significance of V. vulnificus iron-uptake systems. These iron-uptake systems may be attractive candidates for the development of V. vulnificus vaccine. Iron-chelating therapy can also be a promising modality for the prevention and treatment of V. vulnificus infections.
목차
서론
1. 철의 가용성(iron availability)
2. 세균의 철흡수기전
3. 철흡수기전의 발현조절
4. 철과 패혈증 비브리오균 감염증
5. 패혈증 비브리오균의 철흡수기전
6. 가용철 농도에 영향을 미치는 외독소
결론
참고문헌
참고문헌 (66)
참고문헌 신청
1. [학술지(정기간행물)] - Weinberg ED / 1978 / Iron and infection / Microbiol Rev 42 : 45 ~ 66
2. [학술지(정기간행물)] - Bagg A / 1987 / Molecular mechanism of regulation of siderophore-mediated iron assimilation / Microbiol Rev 51 : 509 ~ 518
3. [학술지(정기간행물)] - Neilands JB / 1991 / A brief history of iron metabolism / Biol Met 4 : 1 ~ 6
4. [학술지(정기간행물)] - Gray-Owen SD / 1996 / Bacterial transferrin and lactoferrin receptors / Trends Microbiol 4 : 185 ~ 191
5. [학술지(정기간행물)] - Mey AR / 2001 / Haem utilization in Vibrio cholerae involves multiple TonB-dependent haem receptors / Mol Microbiol 42 : 835 ~ 849
2. [학술지(정기간행물)] - Bagg A / 1987 / Molecular mechanism of regulation of siderophore-mediated iron assimilation / Microbiol Rev 51 : 509 ~ 518
3. [학술지(정기간행물)] - Neilands JB / 1991 / A brief history of iron metabolism / Biol Met 4 : 1 ~ 6
4. [학술지(정기간행물)] - Gray-Owen SD / 1996 / Bacterial transferrin and lactoferrin receptors / Trends Microbiol 4 : 185 ~ 191
5. [학술지(정기간행물)] - Mey AR / 2001 / Haem utilization in Vibrio cholerae involves multiple TonB-dependent haem receptors / Mol Microbiol 42 : 835 ~ 849
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