지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 290 - 295 (6page)
이용수
초록· 키워드
오류제보하기
Monocytes and macrophages regulate host immune system against infectious pathogens. Activated macrophages play an important role in restricting the multiplication and dissemination of pathogens. The concept of alternative activation of macrophages might provide useful insights into pathology of infectious diseases. M1 macrophages (classically activated macrophages) and M2 macrophages (alternatively activated macrophages) are associated with responses to tissue remodeling, pro-inflammatory and anti-inflammatory reactions in various infectious diseases. However, the relevance of macrophage polarization in several infectious diseases was not revealed clearly. Macrophage plasticity and polarization should be considered as a useful conceptual framework for understanding the unknown pathogenesis of infectious diseases. Here we reviewed the recent progress on macrophage polarization and its characters in infectious diseases.
목차
1. 큰포식세포 집단
2. M1과 M2 큰포식세포 특징
3. 세균 감염과 큰포식세포의 극성
4. 결핵균과 큰포식세포
5. 기생충 감염시 대체 활성화 큰포식세포
CLOSING REMARK
REFERENCES
참고문헌 (30)
참고문헌 신청
1. [학술지(정기간행물)] - Gordon S. / 2008 / Elie Metchnikoff : father of natural immunity / Eur J Immunol 38 : 3257 ~ 3264
2. [학술지(정기간행물)] - Nathan CF. / 1983 / Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity / J Exp Med 158 : 670 ~ 689
3. [학술지(정기간행물)] - Abramson SL. / 1990 / IL-4 inhibits superoxide production by human mononuclear phagocytes / J Immunol 144 : 625 ~ 630
4. [학술지(정기간행물)] - Gordon S. / 2003 / Alternative activation of macrophages / Nat Rev Immunol 3 : 23 ~ 35
5. [학술지(정기간행물)] - Mantovani A. / 2005 / Macrophage polarization comes of age / Immunity 23 : 344 ~ 346
2. [학술지(정기간행물)] - Nathan CF. / 1983 / Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity / J Exp Med 158 : 670 ~ 689
3. [학술지(정기간행물)] - Abramson SL. / 1990 / IL-4 inhibits superoxide production by human mononuclear phagocytes / J Immunol 144 : 625 ~ 630
4. [학술지(정기간행물)] - Gordon S. / 2003 / Alternative activation of macrophages / Nat Rev Immunol 3 : 23 ~ 35
5. [학술지(정기간행물)] - Mantovani A. / 2005 / Macrophage polarization comes of age / Immunity 23 : 344 ~ 346
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