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Fabrication and Characterization of Silk/PVA Hydrogels by Sonication and Freezing-Thawing Technique
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초음파와 동결/융해에 의한 실크/PVA 하이드로젤의 제조 및 특성 평가

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Type
Academic journal
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Journal
The Polymer Society Of Korea Polymer Korea Vol.37 No.6 KCI Accredited Journals SCIE
Published
2013.11
Pages
717 - 721 (5page)

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Fabrication and Characterization of Silk/PVA Hydrogels by Sonication and Freezing-Thawing Technique
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Biomaterials like silk fibroin (SF) and poly(vinyl alcohol) (PVA) have received increasing attention in biomedical applications because of their attractive properties such as hydrophobicity and biocompatibility. In this study, efficient systems consisting of interpenetrating SF/PVA hydrogels were prepared as potential candidate for wound dressing applications. A simple approach consisting of sonication and a freezing-thawing technique was adopted to fabricate the hydrogels. Different blend ratios consisting of SF (100, 75, 50, 25 and 0%) with respect to the weight of PVA were prepared. The produced hydrogels were characterized for physico-chemical investigations using various states of techniques like; FE-SEM, TGA, FTIR and tensile strength. The addition of PVA to SF was proved to be beneficial in terms of reducing the pore size and swelling ratio of hydrogels. The mechanical property of SF had been increased by addition of PVA. These results show that SF/PVA hydrogels may serve as potential candidates for wound dressing application.
#hydrogel #poly #silk #sonication #vinyl alcohol

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References (26)

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1. [단행본] - J. Chen / 1997 / Handbook of Biodegradable Polymers / Overseas Publishers Association : 203 ~ google schola 2. [학술지(정기간행물)] - N. A. Peppas / 2000 / / Eur. J. Pram. Biopharm 50 : 27 ~ google schola 3. [학술지(정기간행물)] - 박상준 / 2007 / 조직공학에서 키토산의 활용 / 조직공학과 재생의학 4 (4) : 471 ~ 477 dbpia 4. [학술지(정기간행물)] - K. Burczak / 1994 / / Biomaterials 15 : 231 ~ google schola 5. [학술지(정기간행물)] - T. Hirai / 1996 / / Angew. Makromol. Chem 240 : 213 ~ google schola

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