지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.10
- 수록면
- 530 - 536 (7page)
- DOI
- 10.15188/kjopp.2014.10.28.5.530
이용수
초록· 키워드
오류제보하기
Root barks of Paeonia suffruticosa Andrews (PS) was reported as contraindicated drugs of pregnancy by many Korean medical classics. Recently, a major ingredient component of PS, paeonol was reported that has contraceptive effect on early pregnancy in rats. However, the accurate molecular mechanism is not clear. In this study, we showed that PS decreased the expression of receptor for leukemia inhibitory factor (LIFR) in human endometrial Ishikawa cells at non-toxic dose, although the expression of leukemia inhibitory factor (LIF) was increased by PS. In addition, PS inhibited the adhesion of human trophoblastic JAR cells onto Ishikawa cells. Given importance of LIF-LIFR signaling pathway in the process of embryo implantation, the decreased LIFR expression by PS will be a good explanation on the PS- or its ingredient compounds-induced contraception.
목차
서론
재료 및 방법
결과
고찰
결론
References
참고문헌 (34)
참고문헌 신청
1. [학술지(정기간행물)] - Chung H. / 2000 / Changes in Reproductive Functions in Pregnant Mice Administrated Kyoaekungkue-tang, Bojungkki-tang, Kungso-san, Antae-eum, Antaegumchul-tang / J Korean Oriental Med 21 (3) : 166 ~ 173
2. [학술지(정기간행물)] - Mellin, G. W. / 1962 / The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies / N Engl J Med 267 : 1238 ~ 1244
3. [학술지(정기간행물)] - Jeong J. T. / 1987 / Literatural study On contraindicative drugs during pregnancy / J Oriental Gynecology 1 (1) : 47 ~ 68
4. [단행본] - Kim H.C. / 2001 / Pharmacology on Herbal Medicines / Jipmundang : 47 ~ 150
5. [단행본] - Co-edited by Professors of Herbalogy in Korea / 1991 / Herbalogy / Younglimsa : 193 ~ 195
2. [학술지(정기간행물)] - Mellin, G. W. / 1962 / The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies / N Engl J Med 267 : 1238 ~ 1244
3. [학술지(정기간행물)] - Jeong J. T. / 1987 / Literatural study On contraindicative drugs during pregnancy / J Oriental Gynecology 1 (1) : 47 ~ 68
4. [단행본] - Kim H.C. / 2001 / Pharmacology on Herbal Medicines / Jipmundang : 47 ~ 150
5. [단행본] - Co-edited by Professors of Herbalogy in Korea / 1991 / Herbalogy / Younglimsa : 193 ~ 195
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UCI(KEPA) : I410-ECN-0101-2016-519-000932204