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논문 기본 정보

자료유형
학술저널
저자정보
김정옥 (한국한방산업진흥원) 최혜민 (한국한방산업진흥원) 이희현 (한국한방산업진흥원) 문성옥 (한국한방산업진흥원) 김종범 (한국한방산업진흥원) 이화동 (한국한방산업진흥원)
저널정보
한의병리학회 동의생리병리학회지 동의생리병리학회지 제28권 제3호
발행연도
2014.6
수록면
322 - 329 (8page)
DOI
10.15188/kjopp.2014.06.28.3.322

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초록· 키워드

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The purpose of this study was to investigate the quality of two different commercial Bangpungtongseong-san (BTS) extract granules (BTS-2 and BTS-3) by comparing with BTS decoction (BTS-1). The contents of characterizing components and biological activities of two different commercial BTS extract granules were compared with those of the BTS decoction. The contents of characterizing components were analyzed with HPLC. The antioxidative effects were determined by measuring 2,2-diphenyl-1-picrylhygrazyl (DPPH) radical scavenging and superoxide dismutase (SOD)-like activity. Also, we compared the effects on lipid accumulation and reactive oxygen species (ROS) production during differentiation of 3T3-L1 preadipocytes. The contents of five components except liquiritin and sennoside A were higher in BTS-1. The DPPH radical scavenging and SOD-like activity were higher in BTS-1. BTS-1 significantly inhibited lipid accumulation during differentiation of 3T3-L1 preadipocytes and showed stronger effects than BTS-2, BTS-3. In addition BTS-1 showed stronger inhibition effects on ROS production during differentiation of 3T3-L1 preadipocytes than BTS-2, BTS-3. These results indicate that BTS decoction has strong biological activities than commercial BTS extract granules. It is also consistent with the contents of characterizing components.

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