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자료유형
학술저널
저자정보
Su-Mi Kim (Ministry of Agriculture, Food and Rural Affairs) Hyang-Sim Lee (Ministry of Agriculture, Food and Rural Affairs) Kwang-Nyeong Lee (Ministry of Agriculture, Food and Rural Affairs) Jong-Hyeon Park (Ministry of Agriculture, Food and Rural Affairs) Young-Joon Ko (Ministry of Agriculture, Food and Rural Affairs) Byounghan Kim (Ministry of Agriculture, Food and Rural Affairs)
저널정보
대한미생물학회 JOURNAL OF BACTERIOLOGY AND VIROLOGY JOURNAL OF BACTERIOLOGY AND VIROLOGY Vol.44 No.3
발행연도
2014.9
수록면
269 - 273 (5page)

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초록· 키워드

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Human adenovirus type 5 (hAd5) vectors have been demonstrated to be useful vehicles for gene expressions in animals. However, it has not been reported whether hAd5 transduction might be hampered in the sera of livestock animals in Republic of Korea. We collected 205 samples of livestock animals, such as pig (n=84), cattle (n=84), and goat (n=37) in Korea. The neutralizing antibody (NAb) titers to hAd5 virus were less than 15 in most of samples. Only 8% of goat samples had a NAb titer of 15 or 30. Thus, we showed that hAd5 virus was not neutralized in sera from cattle, pig, and goat, and suggest that the hAd5 vector could be used for the effective delivery of vaccines or proteins in livestock animals in the field.

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INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES

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