지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.12
- 수록면
- 185 - 193 (9page)
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초록· 키워드
오류제보하기
Cancers are based upon an array of orchestrated genetic changes and the identification of changes causally related to the carcinogenic process. To elucidate the mechanism of cancer carcinogenesis, it is necessary to reconstruct these molecular events at each level. Microarray technologies have been extensively used to evaluate genetic alterations associated with cancer onset and progression in clinical oncology. The clinical impact of the genomic alterations identified by microarray technologies are growing rapidly and array analysis has been evolving into a diagnostic tool to better identify high-risk patients and predict patient outcomes from their genomic profiles. Here, we discuss the state-of-the-art microarray technologies and their applications in clinical oncology, and describe the potential benefits of these analysis in the clinical implications and biological insights of cancer biology.
목차
1. Introduction
2. Routine Cytogenetics Diagnostics and Limitations in Oncology
3. Microarray-based Cytogenetic Technology
4. Clinical Application of Microarray Technologies in Oncology
5. Outlook and Concluding Remarks
REFERENCES
참고문헌 (37)
참고문헌 신청
1. [학술지(정기간행물)] - Alizadeh AA / 2000 / Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling / Nature 403 : 503 ~ 511
2. [학술지(정기간행물)] - Bergamaschi A / 2006 / Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer / Genes Chromosomes Cancer 45 : 1033 ~ 1040
3. [학술지(정기간행물)] - Carrasco DR / 2006 / Highresolution genomic profiles define distinct clinicopathogenetic subgroups of multiple myeloma patients / Cancer Cell 9 : 313 ~ 325
4. [학술지(정기간행물)] - Cavallaro S / 2012 / Genomic analysis: toward a new approach in breast cancer management / Crit Rev Oncol Hematol 81 : 207 ~ 223
5. [학술지(정기간행물)] - Chin K / 2006 / Genomic and transcriptional aberrations linked to breast cancer pathophysiologies / Cancer Cell 10 : 529 ~ 541
2. [학술지(정기간행물)] - Bergamaschi A / 2006 / Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer / Genes Chromosomes Cancer 45 : 1033 ~ 1040
3. [학술지(정기간행물)] - Carrasco DR / 2006 / Highresolution genomic profiles define distinct clinicopathogenetic subgroups of multiple myeloma patients / Cancer Cell 9 : 313 ~ 325
4. [학술지(정기간행물)] - Cavallaro S / 2012 / Genomic analysis: toward a new approach in breast cancer management / Crit Rev Oncol Hematol 81 : 207 ~ 223
5. [학술지(정기간행물)] - Chin K / 2006 / Genomic and transcriptional aberrations linked to breast cancer pathophysiologies / Cancer Cell 10 : 529 ~ 541
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UCI(KEPA) : I410-ECN-0101-2016-510-001024186