In this study, as a study for implementing an automotive effectiveness of anti-microbial, anti-fungal, anti-allergen, anti-viral and for considering the operating mechanism based on the activating principle of the anti-substance by the addition of anti-substance to the interior parts of the vehicle such as head lining and carpets, was looking for ways to take advantage of the part. Selection of health-care parts that can exert the maximum effect in a room interior parts to it, and handle the claim for this various material to identify specific effects through the basic material properties verification, was considered to simultaneously satisfied the verification of health-care performance, the reliability of production molded parts and easiness of manufacturing method. In addition, the optimized evaluation method was appropriately selected to the automotive parts through anti-microbial, anti-fungal, anti-allergen and anti-virus performance review and assessment methods.