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논문 기본 정보

자료유형
학술대회자료
저자정보
Minkyu Jeon (Korea Advanced Institute of Science and Technology) Boeun Kim (Korea Advanced Institute of Science and Technology) Mingyu Sung (Korea Advanced Institute of Science and Technology) Jay H. Lee (Korea Advanced Institute of Science and Technology)
저널정보
제어로봇시스템학회 제어로봇시스템학회 국제학술대회 논문집 ICCAS 2014
발행연도
2014.10
수록면
1,534 - 1,539 (6page)

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Identifying the mechanism for and predicting the metabolic shift between lipid accumulation and cell growth is a key research issue for microalgal biodiesel production. In this study, we propose a novel way to integrate a metabolic network model with a semi-empirical model (called “Droop model”) for predicting the lipid accumulation and cell growth simultaneously. At each time instant of mass balance model integration, the Droop model is used to predict the cell growth rate. Then, the Flux Balance Analysis (FBA) model is used to predict the rate of lipid accumulation, which is biochemically consistent with the predicted growth rate. In order to test the validity of the proposed approach, experiments are conducted for growing microalgae specie C. reinhardtii in a batch photo-bioreactor. Droop model’s parameters are estimated using the gathered data and model predictions for the lipid contents are verified. Parameter sensitivity analysis is conducted to investigate how the various parameters affect the cell growth and lipid accumulation.

목차

Abstract
1. INTRODUCTION
2. PROBLEM DEFINITION
3. METHOD
4. RESERT AND DISCUSSION
5. CONCLUSIONS
REFERENCES

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