지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2014.5
- 수록면
- 201 - 205 (5page)
이용수
이 논문의 연구 히스토리 (2)
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Polyvinyl Alcohol-Hydrogel (PVA-H) is a biomaterial used for manufacturing contact lenses as well as for the medium of drug delivery. Previous studies have also showed that PVA-H exhibits superior biocompatibility with hydrophilic elastic nature. The aim of this study is to examine the possible usage of the PVA-H as cartilage replacement material by determining the static and dynamic mechanical properties of PVA-H with different ratios of polyvinyl alcohol (PVA) and phosphate buffered saline (PBS) compositions.
Three different types of PVA-H specimens were made by changing the ratio of PVA (Sigma-Aldrich) and PBS (Sigma-Aldrich) compositions (PVA-H1: 10wt% PVA and 90 wt% PBS; PVA-H2: 20wt% PVA and 80 wt% PBS; PVA-H3: 25 wt% PVA, 45 wt% PBS and DMSO 30 wt%). Static and dynamic tensile tests under the loading frequencies of 0.001, 0.01, 0.1, and 1 Hz were carried out to measure the biomechanical properties of PVA-H1, -H2 within PBS solution and -H3 within PBS/ DMSO solution.
The equilibrium Young"s moduli (EY) of PVA-H1, -H2 and -H3 evaluated from the static displacement control were 84.2±35.1 kPa (n=10), 254±32.2 kPa (n=10) and 588±38.9 kPa (n=5), respectively. The amplitudes of dynamic tensile moduli were varied from 86.3±33.4 kPa (n=10) at 0.001 Hz to 96.9±42.0 kPa (n=10) at 1 Hz for PVA-H1, 282.7±26.4 kPa (n=10) at 0.001 Hz to 309.1±32.2 kPa (n=10) at 1 Hz for PVA-H2 and from 643.8±49.8 kPa (n=10) at 0.001 Hz to 747.7±67.7 kPa (n=5) at 1 Hz for PVA-H3. According to the current results, the frequency dependence of the magnitude of the dynamic modulus confirms the viscoelastic nature of PVA-H material. However, it can be noted that the dynamic modulus increases by up to a factor of 1.15 for PVA-H1, 1.22 for PVA-H2 and 1.27 for PVA-H3, showing insignificant viscoelasticity compared with that for cartilage. The result that static and dynamic moduli of PVA-H3 are larger than those of PVA-H1 and PVA-H2 also suggests that the amount of PVA composition in PVA-H plays an important role in improving both static and dynamic mechanical strengths of PVA-H plays an important role in improving both static and dynamic mechanical strengths of PVA-H material. The phase angle decreased from 5.2±2.1 ˚ at 0.001 Hz to -0.3±1.7 ˚ at 1 Hz for PVA-H1, from 5.6±0.6 ˚ at 0.001 Hz to -0.3±0.7 ˚ at 1 Hz for PVA-H2 and from 8.2±1.1 ˚ at 0.001 Hz to 0.7±0.7 ˚ at 1 Hz for PVA-H3.
Three different types of PVA-H specimens were made by changing the ratio of PVA (Sigma-Aldrich) and PBS (Sigma-Aldrich) compositions (PVA-H1: 10wt% PVA and 90 wt% PBS; PVA-H2: 20wt% PVA and 80 wt% PBS; PVA-H3: 25 wt% PVA, 45 wt% PBS and DMSO 30 wt%). Static and dynamic tensile tests under the loading frequencies of 0.001, 0.01, 0.1, and 1 Hz were carried out to measure the biomechanical properties of PVA-H1, -H2 within PBS solution and -H3 within PBS/ DMSO solution.
The equilibrium Young"s moduli (EY) of PVA-H1, -H2 and -H3 evaluated from the static displacement control were 84.2±35.1 kPa (n=10), 254±32.2 kPa (n=10) and 588±38.9 kPa (n=5), respectively. The amplitudes of dynamic tensile moduli were varied from 86.3±33.4 kPa (n=10) at 0.001 Hz to 96.9±42.0 kPa (n=10) at 1 Hz for PVA-H1, 282.7±26.4 kPa (n=10) at 0.001 Hz to 309.1±32.2 kPa (n=10) at 1 Hz for PVA-H2 and from 643.8±49.8 kPa (n=10) at 0.001 Hz to 747.7±67.7 kPa (n=5) at 1 Hz for PVA-H3. According to the current results, the frequency dependence of the magnitude of the dynamic modulus confirms the viscoelastic nature of PVA-H material. However, it can be noted that the dynamic modulus increases by up to a factor of 1.15 for PVA-H1, 1.22 for PVA-H2 and 1.27 for PVA-H3, showing insignificant viscoelasticity compared with that for cartilage. The result that static and dynamic moduli of PVA-H3 are larger than those of PVA-H1 and PVA-H2 also suggests that the amount of PVA composition in PVA-H plays an important role in improving both static and dynamic mechanical strengths of PVA-H plays an important role in improving both static and dynamic mechanical strengths of PVA-H material. The phase angle decreased from 5.2±2.1 ˚ at 0.001 Hz to -0.3±1.7 ˚ at 1 Hz for PVA-H1, from 5.6±0.6 ˚ at 0.001 Hz to -0.3±0.7 ˚ at 1 Hz for PVA-H2 and from 8.2±1.1 ˚ at 0.001 Hz to 0.7±0.7 ˚ at 1 Hz for PVA-H3.
목차
Abstract
1. 서론
2. 시험편 제조 및 방법
3. 결과
4. 결론 및 고찰
참고문헌
참고문헌 (0)
참고문헌 신청이 논문의 저자 정보
이 논문과 함께 이용한 논문
폴리 ( 4 - 비닐피리딘 ) / 비닐아세테이트 - 비닐알코올 공중합체 블렌드 : 1. 적외선 분광분석에 의한 수소결합 형성에 관한 연구
이준열
,
이혁
,
최동훈
폴리머
1998
.05
Gelatin 존재하에서 Poly ( vinyl alcohol ) ( PVA ) / 붕사 복합체의 동력학적 성질과 결정구조
김명열
폴리머
1988
.08
고검화도의 폴리(비닐 알코올)/디메틸설폭사이드 용액에서의 점성도 특성과 탐침입자의 확산
엄효상
,
박일현
폴리머
2010
.09
폴리 (비닐 알코올) 수용액의 준희박농도 영역에서 사슬 거동에 대한 수소결합의 효과
박일현
,
유영철
,
박기상
외 2명
폴리머
2006
.05
Gelatin 존재하에서의 Poly ( Vinyl Alcohol ) 과 붕사와의 상호작용 (Ⅱ) : Gelatin 존재하에서 얻어진 PVA / Borax 복합체의 구조와 물성
김재문
,
김명열
,
김수경
외 1명
폴리머
1985
.02
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2015-500-002868746