지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.87 No.3
- 발행연도
- 2014.8
- 수록면
- 156 - 160 (5page)
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초록· 키워드
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We report a case of synchronous multiple colon adenocarcinomas in a patient with neurofibromatosis type 1 (NF1). NF1 is an autosomal dominant inherited disorder and patients with NF1 have high risk for both benign and malignant tumors. However, adenocarcinomas involving the colon have rarely been reported in patients with NF1. A 61-year-old man was referred for generalized peritonitis due to descending colon perforation. Left hemicolectomy was performed and pathologic examination showed four adenocarcinomas. Peritoneal nodules were confirmed as metastatic adenocarcinoma (pT4N1M1). The patient also had clinical features compatible with NF1 such as cafe au lait macules, axillary freckles, neurofibromas across the body, and Lisch nodules. Upon review of the literature, colon adenocarcinoma in patients with NF1 tends to occur in males and relatively young age groups, and is associated with advanced tumor stages and multiple colon cancers. To improve treatment outcome, early colonoscopic surveillance should be considered in patients with NF1.
목차
INTRODUCTION
CASE REPORT
DISCUSSION
REFERENCES
참고문헌 (10)
참고문헌 신청
1. [학술지(정기간행물)] - Seminog OO. / 2013 / Risk of benign tumours of nervous system, and of malignant neoplasms, in people with neurofibromatosis : population-based recordlinkage study / Br J Cancer 108 : 193 ~ 198
2. [학술지(정기간행물)] - Kim KJ. / 2002 / A case of colon cancer in a patient with neurofibromatosis type I / Korean J Gastroenterol 40 : 402 ~ 405
3. [학술지(정기간행물)] - Kim SE. / 2002 / Segmentally distributed neurofibromatosis associated with adenocarcinoma of the colon / J Dermatol 29 : 350 ~ 353
4. [학술지(정기간행물)] - Jenkins DH. / 1972 / A case of carcinoma of the colon in association with neurofibromatosis / Br J Surg 59 : 322 ~ 323
5. [학술지(정기간행물)] - Shousha S. / 1981 / Colonic ganglioneuroma : report of a case in a patient with neurofibromatosis, multiple colonic adenomas and adenocarcinoma / Virchows Arch A Pathol Anat Histol 392 : 105 ~ 109
2. [학술지(정기간행물)] - Kim KJ. / 2002 / A case of colon cancer in a patient with neurofibromatosis type I / Korean J Gastroenterol 40 : 402 ~ 405
3. [학술지(정기간행물)] - Kim SE. / 2002 / Segmentally distributed neurofibromatosis associated with adenocarcinoma of the colon / J Dermatol 29 : 350 ~ 353
4. [학술지(정기간행물)] - Jenkins DH. / 1972 / A case of carcinoma of the colon in association with neurofibromatosis / Br J Surg 59 : 322 ~ 323
5. [학술지(정기간행물)] - Shousha S. / 1981 / Colonic ganglioneuroma : report of a case in a patient with neurofibromatosis, multiple colonic adenomas and adenocarcinoma / Virchows Arch A Pathol Anat Histol 392 : 105 ~ 109
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