지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.87 No.2
- 발행연도
- 2014.7
- 수록면
- 94 - 99 (6page)
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초록· 키워드
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Purpose: This study addressed the feasibility and effect of surgical treatment of metachronous periampullary carcinoma after resection of the primary extrahepatic bile duct cancer. The performance of this secondary curative surgery is not well-documented.
Methods: We reviewed, retrospectively, the medical records of 10 patients who underwent pancreaticoduodenectomy (PD) for secondary periampullary cancer following extrahepatic bileduct cancer resection from 1995 to 2011.
Results: The mean age of the 10 patients at the second operation was 61 years (range, 45?70 years). The primary cancers were 7 hilar cholangiocarcinomas, 2 middle common bile duct cancers, and one cystic duct cancer. The secondary cancers were 8 distal common bile duct cancers and 2 carcinomas of the ampulla of Vater. The second operations were 6 Whipple procedures and 4 pylorus-preserving pancreaticoduodenectomies. The mean interval between primary treatment and metachronous periampullary cancer was 20.6 months (range, 3.4?36.6 months). The distal resection margin after primary resection was positive for high grade dysplasia in one patient. Metachronous tumor was confirmed by periampullary pathology in all cases. Four of the 10 patients had delayed gastric emptying (n = 2) or pancreatic fistula (n = 2) after reoperation. There were no perioperative deaths. Median survival after PD was 44.6 months (range, 8.5?120.5 months).
Conclusion: Based on the postoperative survival rate, PD may provide an acceptable protocol for resection in patients with metachronous periampullary cancer after resection of the extrahepatic bile duct cancer.
Methods: We reviewed, retrospectively, the medical records of 10 patients who underwent pancreaticoduodenectomy (PD) for secondary periampullary cancer following extrahepatic bileduct cancer resection from 1995 to 2011.
Results: The mean age of the 10 patients at the second operation was 61 years (range, 45?70 years). The primary cancers were 7 hilar cholangiocarcinomas, 2 middle common bile duct cancers, and one cystic duct cancer. The secondary cancers were 8 distal common bile duct cancers and 2 carcinomas of the ampulla of Vater. The second operations were 6 Whipple procedures and 4 pylorus-preserving pancreaticoduodenectomies. The mean interval between primary treatment and metachronous periampullary cancer was 20.6 months (range, 3.4?36.6 months). The distal resection margin after primary resection was positive for high grade dysplasia in one patient. Metachronous tumor was confirmed by periampullary pathology in all cases. Four of the 10 patients had delayed gastric emptying (n = 2) or pancreatic fistula (n = 2) after reoperation. There were no perioperative deaths. Median survival after PD was 44.6 months (range, 8.5?120.5 months).
Conclusion: Based on the postoperative survival rate, PD may provide an acceptable protocol for resection in patients with metachronous periampullary cancer after resection of the extrahepatic bile duct cancer.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (29)
참고문헌 신청
1. [학술지(정기간행물)] - Lindell G. / 2000 / Operations for extrahepatic bile duct cancers : are the results really improving? / Eur J Surg 166 : 535 ~ 539
2. [학술지(정기간행물)] - Miyakawa S. / 2009 / Biliary tract cancer treatment : 5, 584 results from the Biliary Tract Cancer Statistics Registry from 1998 to 2004 in Japan / J Hepatobiliary Pancreat Surg 16 : 1 ~ 7
3. [학술지(정기간행물)] - Hori H. / 2006 / Double cancer of gall bladder and bile duct not associated with anomalous junction of the pancreaticobiliary duct system / Jpn J Clin Oncol 36 : 638 ~ 642
4. [학술지(정기간행물)] - Kurosaki I. / 1997 / Synchronous primary tumors of the extrahepatic bile duct and gallbladder / J Surg Oncol 65 : 258 ~ 262
5. [학술지(정기간행물)] - Gertsch P. / 1990 / Multiple tumors of the biliary tract / Am J Surg 159 : 386 ~ 388
2. [학술지(정기간행물)] - Miyakawa S. / 2009 / Biliary tract cancer treatment : 5, 584 results from the Biliary Tract Cancer Statistics Registry from 1998 to 2004 in Japan / J Hepatobiliary Pancreat Surg 16 : 1 ~ 7
3. [학술지(정기간행물)] - Hori H. / 2006 / Double cancer of gall bladder and bile duct not associated with anomalous junction of the pancreaticobiliary duct system / Jpn J Clin Oncol 36 : 638 ~ 642
4. [학술지(정기간행물)] - Kurosaki I. / 1997 / Synchronous primary tumors of the extrahepatic bile duct and gallbladder / J Surg Oncol 65 : 258 ~ 262
5. [학술지(정기간행물)] - Gertsch P. / 1990 / Multiple tumors of the biliary tract / Am J Surg 159 : 386 ~ 388
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UCI(KEPA) : I410-ECN-0101-2015-510-002473383