지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.6
- 수록면
- 6 - 11 (6page)
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The sentinel node (SN) concept has revolutionized surgery for both melanoma and breast cancer over the past two decades. The clinical utility of the SN concept has been confirmed, and individualized treatment based on the status of SNs is well accepted in breast cancer. However, the clinical application of SN navigation surgery (SNNS) for gastric cancer has remained highly controversial during last decade due to the complexity of lymphatic flow in the stomach. A recent meta-analysis and prospective multicenter studies have shown an acceptable rate of detection of SNs and a high accuracy in determining SN status. At present, a dual tracer method using radioactive colloid and vital dye is considered the best means to detect SNs in gastric cancer. Nonetheless, new technologies such as near infrared imaging and fluorescence imaging using indocyanine green have potential to improve the quality of SNNS and change the treatment strategy for gastric cancer. Additionally, rapid intraoperative immunohistochemical staining and intraoperative real-time reverse transcription polymerase chain reaction assay can be used to supplement traditional hematoxylin-eosin staining. In the near future, minimally invasive, function-preserving procedures based on SN mapping of the stomach will likely become increasingly utilized. Herein, the current status of SNNS and individualized treatments for gastric cancer are reviewed.
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UCI(KEPA) : I410-ECN-0101-2015-510-002475256