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논문 기본 정보

자료유형
학술저널
저자정보
Mi-Hwa Jung (경북대학교) Jae-Mok Lee (경북대학교)
저널정보
대한치과재료학회 대한치과재료학회지 대한치과재료학회지 제41권 제2호
발행연도
2014.6
수록면
145 - 153 (9page)
DOI
10.14815/kjdm.2014.41.2.145

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초록· 키워드

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The purpose of this study was to quantify the expressions of XO and MDA in the gingival tissues of the chronic periodontitis patients associated with HTN. Xanthine oxidase (XO) generates reactive oxygen species. Malondialdehyde (MDA) is one of many low molecular weight end-products of LPO and is the most often measured as an index of peroxidation. Depending on the patient"s systemic condition and clinical criteria of gingiva, each gingival sample was divided into three groups. Group 1 is clinically healthy gingiva. Group 2 is inflamed gingiva from patients with chronic periodontitis. Group 3 is inflamed gingiva from patients with chronic periodontitis associated with HTN. The expression levels of XO increased in order of group 1, group 2 and group 3, and significantly increased in group 3 as compared to group 1. The expression levels of MDA increased in order of group 1, group 2 and group 3. MDA expression was significantly higher in group 2 than in group 1, and the quantitative analysis of MDA level was significantly higher in group 3 than in group 1. In conclusion, this study demonstrated that the expression levels of XO and MDA might be inflammatory and bone resorption marker in periodontal inflammed tissue. It is assumed that hypertension may be associated with the progression of periodontal inflammation and alveolar bone resorption.

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ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
SUMMARY
REFERENCES

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