지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Periodic analysis of local epidemiologic data of prevalent pathogens of blood culture can provide clinicians with relevant information to guide empirical antibiotic therapy. In this study, we analyzed a pattern of change of causative microorganisms and antimicrobial resistance at a tertiary medical center in Chungcheong province from 2003 to 2012, retrospectively. Of 70,258 blood specimens cultured, 6,063 (8.6%) were positive. Among the positive isolates, 95.9% were aerobic or facultative anaerobic bacteria, 0.1% were anaerobes, and 3.9% were fungi. Coagulase-negative Staphylococci (CoNS) (32.9%), Escherichia coli (16.7%), Staphylococcus aureus (9.1%), Klebsiella pneumoniae (6.4%), and α-hemolytic Streptococcus (5.9%) were commonly isolated bacteria, and Candida albicans (1.4%) was the most commonly isolated fungi. Enterococcus faecium progressively increased but Streptococcus pneumoniae, Acinetobacter baumannii and Proteus species gradually decreased over a period of 10 years. The multidrug-resistant microorganisms such as methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), cefotaxime-resistant E. coli, imipenem-resistant Pseudomonas aeruginosa (IRPA) and imipenem-resistant A. baumannii (IRAB), were significantly increased. Therefore, there is a need for a more strict control of antibiotics and a more updated guideline for the treatment of bloodstream infection.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (32)
참고문헌 신청
1. [학술지(정기간행물)] - 안균열 / 2006 / 환자의 혈액배양에서 분리된 균종과 항균제 감수성의 변화추이 / Annals of Clinical Microbiology 9 (1) : 42 ~ 50
2. [학술지(정기간행물)] - Alvarez-Lerma F / 1996 / Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit / Intensive Care Med 22 : 387 ~ 394
3. [학술지(정기간행물)] - Behrendt G / 1999 / Influence of antimicrobial treatment on mortality in septicemia / J Chemother 11 : 179 ~ 186
4. [학술지(정기간행물)] - Boyce JM / 1994 / Outbreak of multidrug-resistant Enterococcus faecium with transferable vanB class vancomycin resistance / J Clin Microbiol 32 : 1148 ~ 1153
5. [학술지(정기간행물)] - Bush K / 2001 / New β-lactamases in gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy / Clin Infec Dis 32 : 1085 ~ 1089
2. [학술지(정기간행물)] - Alvarez-Lerma F / 1996 / Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit / Intensive Care Med 22 : 387 ~ 394
3. [학술지(정기간행물)] - Behrendt G / 1999 / Influence of antimicrobial treatment on mortality in septicemia / J Chemother 11 : 179 ~ 186
4. [학술지(정기간행물)] - Boyce JM / 1994 / Outbreak of multidrug-resistant Enterococcus faecium with transferable vanB class vancomycin resistance / J Clin Microbiol 32 : 1148 ~ 1153
5. [학술지(정기간행물)] - Bush K / 2001 / New β-lactamases in gram-negative bacteria: diversity and impact on the selection of antimicrobial therapy / Clin Infec Dis 32 : 1085 ~ 1089
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