지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.6
- 수록면
- 73 - 78 (6page)
이용수
초록· 키워드
오류제보하기
According to WHO global estimates from 2008, more than 1.4 billion adults were overweight and among them, over 200 million men and 300 million women were obese. Although the main treatment modalities for overweight and obese individuals remain dieting and physical exercise, the synthetic anti-obesity medications have been increasingly used due to their perceived convenience. Generally, anti-obesity medications are classified as appetite suppressants or fat absorption blockers. In the present study, we examined the adverse side-effects in respect of behavior changes of phentermine and Ephedra sinica (mahuang) that are anti-obesity drugs currently distributed to domestic consumers. Phentermine is mainly classified as an anorexing agent and mahuang a thermogenic agent. Because phentermine and mahuang are considered to display effectiveness through the regulation of nerve system, their potential influences of on behavioral changes were examined employing animal experiments. From the results of experiments testing locomotor activity through the use of treadmill, rota-rod, and open field system, phentermine and mahuang were commonly revealed to induce behavioral changes of rats by reducing a motor ability, an ability to cope with an external stimulus, and a sense of balance or by augmenting wariness or excitement. These adverse effects of phenternime and mahuang in behavioral changes need to be identified in humans and anti-obesity medications such as phentermine and mahuang should be prescribed for only obesity where it is anticipated that the benefits of the treatment outweigh their potential risks.
목차
Materials and Methods
Results
Discussion
References
참고문헌 (25)
참고문헌 신청
1. [학술지(정기간행물)] - Bianco AC. / 2013 / The role of thyroid hormone and brown adipose tissue in energy homoeostasis / Lancet Diabetes Endocrinol 1 (3) : 250 ~ 258
2. [학술지(정기간행물)] - Lavie CJ. / 2009 / Obesity and cardiovascular disease : risk factor, paradox, and impact of weight loss / J Am Coll Cardiol 53 (21) : 1925 ~ 1932
3. [학술지(정기간행물)] - Steppan CM. / 2001 / The hormone resistin links obesity to diabetes / Nature 409 (6818) : 307 ~ 312
4. [학술지(정기간행물)] - Curioni CC. / 2005 / Long-term weight loss after diet and exercise : a systematic review / Int J Obes(Lond) 29 (10) : 1168 ~ 1174
5. [학술지(정기간행물)] - Kelley GA. / 2013 / Effects of exercise in the treatment of overweight and obese children and adolescents : a systematic review of meta-analyses / J Obes 2013 : 783103 ~
2. [학술지(정기간행물)] - Lavie CJ. / 2009 / Obesity and cardiovascular disease : risk factor, paradox, and impact of weight loss / J Am Coll Cardiol 53 (21) : 1925 ~ 1932
3. [학술지(정기간행물)] - Steppan CM. / 2001 / The hormone resistin links obesity to diabetes / Nature 409 (6818) : 307 ~ 312
4. [학술지(정기간행물)] - Curioni CC. / 2005 / Long-term weight loss after diet and exercise : a systematic review / Int J Obes(Lond) 29 (10) : 1168 ~ 1174
5. [학술지(정기간행물)] - Kelley GA. / 2013 / Effects of exercise in the treatment of overweight and obese children and adolescents : a systematic review of meta-analyses / J Obes 2013 : 783103 ~
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2015-500-001679210