Since the accident of hydrogen fluoride release in 2012, there have been frequent chemical leaks. Particularly, acidic chemicals like sulfuric acid, nitric acid and hydrogen chloride take up 37% of the total chemical accidents which took place for the past 10 years. When an acidic chemical leak happens, fume is generated, diffusing into the air, which might cause serious damage to health of local residents and the environment. However, there is no enough reference data for production and using of acidic chemicals. In this study, we investigated characteristics of production and using for acidic chemicals with high accident frequency. As a results, domestic chemical accidents were categorized according to chemical types and production, using, and handling characteristics of acidic chemicals were identified. sulfuric acid was handled in the largest amount, followed in the order of hydrogen chloride, nitric acid, acrylic acid, and hydrogen fluoride. Sulfuric acid is used in the industry of manufacturing composite fertilizer and mainly used for manufacturing fertilizer. Hydrogen chloride are used in the industry of manufacturing basic chemicals for petrochemical family and mainly used for pH regulator. It is expected that this results could be used as preliminary data for making decisions on facilities required intensive management in order to prevent chemical accidents and prepare countermeasures against such accidents.