지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.4
- 수록면
- 163 - 168 (6page)
이용수
초록· 키워드
오류제보하기
Wnt proteins are a family of secreted glycoproteins that are evolutionarily conserved and considered to be involved in extensive developmental processes in metazoan organisms. The characterization of wnt genes may improve understanding the parasite’s development. In the present study, a wnt4 gene encoding 491amino acids was amplified from cDNA of metacestodes of Taenia solium using reverse transcription PCR (RT-PCR). Bioinformatics tools were used for sequence analysis. The conserved domain of the wnt gene family was predicted. The expression profile of Wnt4 was investigated using real-time PCR. Wnt4 expression was found to be dramatically increased in scolex evaginated cysticerci when compared to invaginated cysticerci. In situ hybridization showed that wnt4 gene was distributed in the posterior end of the worm along the primary body axis in evaginated cysticerci. These findings indicated that wnt4 may take part in the process of cysticerci evagination and play a role in scolex/bladder development of cysticerci of T. solium.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (32)
참고문헌 신청
Flisser A / 2005 / WHO/FAO/OIE, Guidelines for the Surveillance, Prevention and Control of Taeniosis/Cysticercosis / Office International des Epizooties :1~9
Sciutto E / 2000 / Taenia solium disease in humans and pigs : an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions / Microbes Infect 2:1875~1890
Larralde C / 1992 / Seroepidemiology of cysticercosis in Mexico / Salud Publica Mex 34:197~210
Toledo A / 2001 / Two epitopes shared by Taenia crassiceps and Taenia solium confer protection against murine T. crassiceps cysticercosis along with a prominent T1 response / Infect Immun 69:1766~1773
Port F / 2010 / Wnt trafficking : new insights into Wnt maturation, secretion and spreading / Traffic 11:1265~1271
Sciutto E / 2000 / Taenia solium disease in humans and pigs : an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions / Microbes Infect 2:1875~1890
Larralde C / 1992 / Seroepidemiology of cysticercosis in Mexico / Salud Publica Mex 34:197~210
Toledo A / 2001 / Two epitopes shared by Taenia crassiceps and Taenia solium confer protection against murine T. crassiceps cysticercosis along with a prominent T1 response / Infect Immun 69:1766~1773
Port F / 2010 / Wnt trafficking : new insights into Wnt maturation, secretion and spreading / Traffic 11:1265~1271
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2015-510-001432013