지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.12
- 수록면
- 75 - 82 (8page)
이용수
초록· 키워드
오류제보하기
Objectives The aim of this study was to determine the association between low-level mercury exposure and neurobehavioral functions in adults living in coastal regions of Korea.
Methods We selected 172 adults aged 20-65 years living in a city in the coastal region of Korea. A sociodemographic survey was conducted, mercury levels in the blood, urine, and hair were measured, and the associations according to computerized neurobehavioral tests were determined using univariate analysis. After adjustment for associated variables, a multivariate linear regression analysis was performed.
Results The geometric mean mercury levels in the blood, urine, and hair were 5.41 ㎍/L (range, 0.00-15.84 ㎍/L), 1.17 ㎍/g-creatinine (range, 0.00-32.86 ㎍/g-creatinine), and 1.37 ㎎/㎏ (range, 0.42-6.56 ㎎/㎏), respectively. Variables that were associated with simple reaction time according to the neurobehavioral test results were age and urine mercury level. Variables associated with choice reaction time were the recent use of Korean traditional medicine and urine mercury level. Variables associated with the right-hand finger tapping speed test were age, gender, smoking behavior, education level, monthly household income, and urine mercury level. Variables associated with the left-hand finger tapping speed test were age, gender, education level, and urine mercury level. After adjustment for associated variables, there was no significant association between urine mercury level and simple reaction time (β=25.96; p =0.47), choice reaction time (β=50.37; p =0.32), or the number of left-hand finger taps (β=-1.54; p =0.21). However, urine mercury level was significantly associated with the number of right-hand finger taps (β=-3.86; p =0.01).
Conclusions We found no evidence that low-level mercury exposure in adults is associated with deficits in neurobehavioral functions. A longer follow-up study is required to confirm this conclusion.
Methods We selected 172 adults aged 20-65 years living in a city in the coastal region of Korea. A sociodemographic survey was conducted, mercury levels in the blood, urine, and hair were measured, and the associations according to computerized neurobehavioral tests were determined using univariate analysis. After adjustment for associated variables, a multivariate linear regression analysis was performed.
Results The geometric mean mercury levels in the blood, urine, and hair were 5.41 ㎍/L (range, 0.00-15.84 ㎍/L), 1.17 ㎍/g-creatinine (range, 0.00-32.86 ㎍/g-creatinine), and 1.37 ㎎/㎏ (range, 0.42-6.56 ㎎/㎏), respectively. Variables that were associated with simple reaction time according to the neurobehavioral test results were age and urine mercury level. Variables associated with choice reaction time were the recent use of Korean traditional medicine and urine mercury level. Variables associated with the right-hand finger tapping speed test were age, gender, smoking behavior, education level, monthly household income, and urine mercury level. Variables associated with the left-hand finger tapping speed test were age, gender, education level, and urine mercury level. After adjustment for associated variables, there was no significant association between urine mercury level and simple reaction time (β=25.96; p =0.47), choice reaction time (β=50.37; p =0.32), or the number of left-hand finger taps (β=-1.54; p =0.21). However, urine mercury level was significantly associated with the number of right-hand finger taps (β=-3.86; p =0.01).
Conclusions We found no evidence that low-level mercury exposure in adults is associated with deficits in neurobehavioral functions. A longer follow-up study is required to confirm this conclusion.
목차
Introduction
Materials and Methods
Results
Discussion
References
참고문헌 (30)
참고문헌 신청
World Health Organization / Guidance for identifying populations at risk from mercury exposure
Harada M. / 1995 / Minamata disease: methylmercury poisoning in Japan caused by environmental pollution / Crit Rev Toxicol 25(1):1~24
Bakir F / 1973 / Methylmercury poisoning in Iraq / Science 18(4096):230~241
International Programme on Chemical Safety / Environmental health criteria 101: methylmercury; 1990
National Research Council / Toxicological effects of methylmercury; 2000
Harada M. / 1995 / Minamata disease: methylmercury poisoning in Japan caused by environmental pollution / Crit Rev Toxicol 25(1):1~24
Bakir F / 1973 / Methylmercury poisoning in Iraq / Science 18(4096):230~241
International Programme on Chemical Safety / Environmental health criteria 101: methylmercury; 1990
National Research Council / Toxicological effects of methylmercury; 2000
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UCI(KEPA) : I410-ECN-0101-2015-530-001447483