지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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The effect of Sopung-tang(SPT) and trans-cranial direct current stimulation(tDCS) was investigated in photothrombotic brain infarction(PTI) rats. Sprague-Dawley 80 rats, were divided into four groups. group Ⅰ was experiental control group(n=20), group Ⅱ was PTI induced and oral administration of SPT(n=20), group Ⅲ was PTI induced and tDCS administration(n=20) and group Ⅳ was PTI induced and SPT and tDCS administration for 28 days on stroke rats(n=20). Analysis the neurological function test, 25 point behavior functional score test, and immunohistochemistric finding of GDNF expression, and electron microscopy assessment In motor behavior test, the outcome of group Ⅳ was significantly difference than the other group, and In immunohistochemistric finding, group Ⅱ, Ⅲ, Ⅳ were increase GDNF expression on 28 days, In electron microscopy finding, the all groups were degenerated of cell organelles, and synaptic plasticity were improvement of group Ⅱ, Ⅲ, Ⅳ(especially group Ⅳ) These results suggest that, 28days application of SPT and tDCS was the motor function and histopathologic, micro-morphological improvement of motor function recovery and positive influence on synaptic plasticity.
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참고문헌
참고문헌 (33)
참고문헌 신청
전국한의과대학심계내과교실 / 1996 / 심계내과학 / 군자출판사 :331
김헌수 / 2006 / 광화학적 허혈성 뇌경색 쥐 모델에서 행동평가의 유용성 / Annals of Rehabilitation Medicine 30(2):135~141
Sigler, A. / 2008 / Hardware and methodology for targeting single brain arterioles for photothrombotic stroke on an upright microscope / Journal Neuroscience Methods 170(1):35~44
Yuh, W. T. C. / 1999 / The need for objective assessment of the new imaging techniques and understanding the expanding roles of stroke imaging / AJNR 20:1779~1784
Fisher, M. / 2004 / The ischemic penumbra : identification, evolution and treatment concept / Cerebrovasc Dis 17(1):1~6
김헌수 / 2006 / 광화학적 허혈성 뇌경색 쥐 모델에서 행동평가의 유용성 / Annals of Rehabilitation Medicine 30(2):135~141
Sigler, A. / 2008 / Hardware and methodology for targeting single brain arterioles for photothrombotic stroke on an upright microscope / Journal Neuroscience Methods 170(1):35~44
Yuh, W. T. C. / 1999 / The need for objective assessment of the new imaging techniques and understanding the expanding roles of stroke imaging / AJNR 20:1779~1784
Fisher, M. / 2004 / The ischemic penumbra : identification, evolution and treatment concept / Cerebrovasc Dis 17(1):1~6
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