지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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The purpose of this study is to investigate whether the intracellular hydrogen peroxide productions of mouse macrophage RAW 264.7 are modulated by Red Ginseng-Ejung-tang water extract (ER) and White Ginseng-Ejung-tang water extract (EG). Red Ginseng-Ejung-tang were composed of Red Ginseng, Atractylodes rhizome white, Zingiberis Rhizoma Siccus, and Glycyrrhizae Radix. White Ginseng-Ejung-tang were composed of White Ginseng, Atractylodes rhizome white, Zingiberis Rhizoma Siccus, and Glycyrrhizae Radix. The intracellular hydrogen peroxide productions were measured by dihydrorhodamine 123 assay with spectrofluorometer (excitation 485 nm; emission 535 nm). For 4, 20, 24, 44, 48, 68, and 72 h incubation, ER significantly increased hydrogen peroxide productions of RAW 264.7 at the concentration of 25, 50, 100, and 200 μg/mL (P <0.05). EG for 4, 20, 24, 44, and 48 h incubation significantly increased hydrogen peroxide productions of RAW 264.7 at the concentration of 25, 50, 100, and 200 μg/mL (P <0.05). For 68 and 72 h incubation, EG at the concentration of 50, 100, and 200 μg/mL significantly increased hydrogen peroxide productions in RAW 264.7 (P <0.05). These results suggest that ER and EG have the immune-enhancing properties related with their increasing effects on the intracellular hydrogen peroxide production of macrophage.
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참고문헌
참고문헌 (20)
참고문헌 신청
1. [단행본] - 廣州中醫學院 / 1990 / 영림사 / 영림사
2. [단행본] - 황도연 / 1992 / 대역증맥 방약합편 / 남산당 : 127 ~ 128
3. [학술지(정기간행물)] - Guiñazú, N. / 2010 / Induction of NADPH oxidase activity and reactive oxygen species production by a single Trypanosoma cruzi antigen / Int J Parasitol 40 (13) : 1531 ~ 1538
4. [학술지(정기간행물)] - Newman, S.L / 1999 / Macrophages in host defense against Histoplasma capsulatum / Trends Microbiol 7 (2) : 67 ~ 71
5. [학술지(정기간행물)] - Supek, F / 1997 / Function of metal-ion homeostasis in the cell division cycle, mitochondrial protein processing, sensitivity to mycobacterial infection and brain function / J Exp Biol 200 (Pt 2) : 321 ~ 330
2. [단행본] - 황도연 / 1992 / 대역증맥 방약합편 / 남산당 : 127 ~ 128
3. [학술지(정기간행물)] - Guiñazú, N. / 2010 / Induction of NADPH oxidase activity and reactive oxygen species production by a single Trypanosoma cruzi antigen / Int J Parasitol 40 (13) : 1531 ~ 1538
4. [학술지(정기간행물)] - Newman, S.L / 1999 / Macrophages in host defense against Histoplasma capsulatum / Trends Microbiol 7 (2) : 67 ~ 71
5. [학술지(정기간행물)] - Supek, F / 1997 / Function of metal-ion homeostasis in the cell division cycle, mitochondrial protein processing, sensitivity to mycobacterial infection and brain function / J Exp Biol 200 (Pt 2) : 321 ~ 330
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