지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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The present study was conducted with the object of examining how ST36 and LR3 electro acupuncture affects the injured side and the intact side in rats with sciatic nerve injury. For this study, we divided rats into a control group that were injured but not treated, experimental group I that were injured and had electro acupuncture on the intact side, experimental group II that were injured and had electro?acupuncture on the injured side, and experimental group III that were injured and had electro?acupuncture on both the intact side and the injured side, and performed behavioral and immunohistochemical tests. The results of this study are as follows. In the results of hot plate test, on Day 1 of experiment, experimental group I did not show a statistically significant difference but experimental group II and III showed a statistically significant difference, and on Day 2 and 3, all of experimental group I, II and III showed a statistically significant difference. In the results of SFI test, on Day 7 of experiment, experimental group I did not show a statistically significant difference but experimental group II and III showed a statistically significant difference, and on Day 14 and 21, all of experimental group I, II and III showed a statistically significant difference. In the results of immunohistochemical test, the expression of c-fos decreased gradually on Day 1, 2 and 3 in all the experimental groups, and the decrease was larger in the experimental groups that had electro?acupuncture than in the control group. In the results of immunohistochemical test, the expression of BDNF increased gradually on Day 7, 14 and 21 in all the experimental groups, and the expression was higher in the experimental groups than in the control group. Summing up the results, ST36 and LR3 electro acupuncture was effective when it was applied to the injured side and to both sides after sciatic nerve injury, but it was also effective in pain relief and nerve regeneration when it was applied to the intact side.
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참고문헌 (40)
참고문헌 신청
1. [학술지(정기간행물)] - Mearow, K. M / 1998 / The effects of NGF and sensory nerve stimulation on collateral sprouting and gene expression in adult sensory neurons / Exp Neurol 15 (1) : 14 ~ 25
2. [학술지(정기간행물)] - Rodriguez, F. J. / 2004 / Regeneration and functional recovery following peripheral nerve injury / Drug Discov Today Dis Models 1 (2) : 177 ~ 185
3. [학술지(정기간행물)] - Zimmermann, M / 2001 / Pathobiology of neuropathic pain / Eur J Pharmacol 429 (1) : 23 ~ 37
4. [학술지(정기간행물)] - Mackinnon, S. E. / 1985 / Histologic assessment of nerve regeneration in the rat / Plast Reconstr Surg 75 (3) : 384 ~ 388
5. [학술지(정기간행물)] - Mannheimer, C. / 1978 / The effect of transcutaneous electrical nerve stimulation(TNS)on joint pain in patients with rheumatoid arthritis / Scand J Rheumatol 7 (1) : 13 ~ 16
2. [학술지(정기간행물)] - Rodriguez, F. J. / 2004 / Regeneration and functional recovery following peripheral nerve injury / Drug Discov Today Dis Models 1 (2) : 177 ~ 185
3. [학술지(정기간행물)] - Zimmermann, M / 2001 / Pathobiology of neuropathic pain / Eur J Pharmacol 429 (1) : 23 ~ 37
4. [학술지(정기간행물)] - Mackinnon, S. E. / 1985 / Histologic assessment of nerve regeneration in the rat / Plast Reconstr Surg 75 (3) : 384 ~ 388
5. [학술지(정기간행물)] - Mannheimer, C. / 1978 / The effect of transcutaneous electrical nerve stimulation(TNS)on joint pain in patients with rheumatoid arthritis / Scand J Rheumatol 7 (1) : 13 ~ 16
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