지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Oryeong-san which was first recorded in Shanghanrun describing the treatments of acute febrile disease is one of the frequently used oriental medicines. Oryeong-san has been prescribed for the treatment of symptoms accompanied by edema. The purpose of this study was to examine the diuretic effects of Oryeong-san by different routes of administration. Oryeong-san (100 mg/kg body weight) was administrated by three different routes in Sprague-Dawley rats: intravenous infusion, intraperitoneal injection and oral intake. Oral intake of Oryeong-san significantly increased urinary volume and excretion of Na<SUP>+</SUP>, Cl<SUP>-</SUP>, and K<SUP>+</SUP> compared to vehicle-treated control group. The effects were concentration-dependent. Intravenously administrated Oryeong-san increased urinary volume and electrolyte excretion but without significance in hydrated (0.02 ml/min/rat for 90 min) anesthetized rats. Similarly, intraperitoneally injected Oryeong-san had no effects on water and urine electrolyte excretion compared with saline control group. These findings suggest that Oryeong-san has different effects on water and electrolyte balance by routes of administration.
목차
Introduction
Materials and Methods
Results
Discussion
References
참고문헌 (11)
참고문헌 신청
1. [학술지(정기간행물)] - Chen, D. A / 1998 / Treating 27 cases of edema in the lower limbs with Wu Ling San / Xinjiang J Tradit Chin Med 16 (1) : 19 ~ 20
2. [학술지(정기간행물)] - Liu, Q. L. / 2001 / Effectiveness of a traditional Chinese medicine, Wulingsan, in suppressing the development of nephrocalcinosis induced by a high phosphorus diet in young rats / Med Electron Microsc 34 (2) : 103 ~ 114
3. [학술지(정기간행물)] - Yoshimuraa, K. / 1998 / Investigation of the Possible role of sialic acid in calcium oxalate urolithiasis / Eur Urol 33 (1) : 111 ~ 115
4. [학술지(정기간행물)] - Tsai, C. H. / 2008 / A traditional Chinese herbal antilithic formula, Wulingsan, effectively prevents the renal deposition of calcium oxalate crystal in ethylene glycol-fed rats / Urol Res 36 (1) : 17 ~ 24
5. [학술지(정기간행물)] - Hattori, T. / 1997 / Sairei-to may inhibit the synthesis of endothelin-1 in nephritic glomeruli / Nippon Jinzo Gakkai Shi 39 (2) : 121 ~ 128
2. [학술지(정기간행물)] - Liu, Q. L. / 2001 / Effectiveness of a traditional Chinese medicine, Wulingsan, in suppressing the development of nephrocalcinosis induced by a high phosphorus diet in young rats / Med Electron Microsc 34 (2) : 103 ~ 114
3. [학술지(정기간행물)] - Yoshimuraa, K. / 1998 / Investigation of the Possible role of sialic acid in calcium oxalate urolithiasis / Eur Urol 33 (1) : 111 ~ 115
4. [학술지(정기간행물)] - Tsai, C. H. / 2008 / A traditional Chinese herbal antilithic formula, Wulingsan, effectively prevents the renal deposition of calcium oxalate crystal in ethylene glycol-fed rats / Urol Res 36 (1) : 17 ~ 24
5. [학술지(정기간행물)] - Hattori, T. / 1997 / Sairei-to may inhibit the synthesis of endothelin-1 in nephritic glomeruli / Nippon Jinzo Gakkai Shi 39 (2) : 121 ~ 128
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