지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Herbal medicines are medicinal products containing a single or a mixture of two or more different herbal substances or herbal preparations as active principles. Recently, much attention has been paid to developing various kinds of fermented herbal extracts, a new type of traditional herbal medicine in the field of Korean traditional medicine. The fermentation of medicinal herbs is intended to exert a favorable influence on bioestability, bioavaliablilty and pharmacological activity of herbal extract in the gastrointestinal tract as well as intensifying the nutritional and pharmacological aspects of the medicinal herbs. The purpose of this study was to investigate biological activities of fermented Rehmanniae Radix by lactic acid bacteria at 30℃ for 3 days in comparison with those for Rehmanniae Radix The fermented Rehmanniae Radix exhibited different chemical profile to Rehmanniae Radix generated with HPLC, indicating production of new ingredients during fermentation. Rehmanniae Radix served as good nutritional sources for the growth of lactic acid bacteria showing increased number of bacteria during fermentation. Toxic effect of the fermented Rehmanniae Radix to cells were not seen judged by the MTT assay. The fermented Rehmanniae Radix exhibited better antioxidant effect than non-fermented Rehmanniae Radix analyzed by a SOD-likely assay. Both hypoglycemic and hypotensive effects of the fermented Rehmanniae Radix were also detected and better than those for Rehmanniae Radix in showing dose-dependent inhibitory effects on alpha-glucosidase and ACE, respectively. In conclusion, fermented Rehmanniae Radix appears to have more biological activities than non-feremented Rehmanniae Radix showing not only antioxidant effect but also cardiovascular protection.
목차
서론
재료 및 방법
결과
고찰 및 결론
참고문헌
참고문헌 (40)
참고문헌 신청
1. [단행본] - 이상인 / 1981 / 본초학 / 수서원 : 47 ~ 110
2. [단행본] - 鄒澍 / 2001 / 본경소증 상 / 대성의학사 : 50 ~ 54
3. [단행본] - 안덕균 / 1998 / 중약대사전(1) / 도서출판 정담 : 129 ~ 135
4. [학술지(정기간행물)] - Morota, T. / 1989 / Two iridoid glycosides from Reridoia glutinosa / Phytochemistry 28 : 2149 ~ 2153
5. [학술지(정기간행물)] - 송효인 / 2007 / 베타아밀로이드로 유도된 신경세포사멸에 대한 地黃 및 地黃食醋의 보호효과 / 동의생리병리학회지 21 (1) : 190 ~ 198
2. [단행본] - 鄒澍 / 2001 / 본경소증 상 / 대성의학사 : 50 ~ 54
3. [단행본] - 안덕균 / 1998 / 중약대사전(1) / 도서출판 정담 : 129 ~ 135
4. [학술지(정기간행물)] - Morota, T. / 1989 / Two iridoid glycosides from Reridoia glutinosa / Phytochemistry 28 : 2149 ~ 2153
5. [학술지(정기간행물)] - 송효인 / 2007 / 베타아밀로이드로 유도된 신경세포사멸에 대한 地黃 및 地黃食醋의 보호효과 / 동의생리병리학회지 21 (1) : 190 ~ 198
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UCI(KEPA) : I410-ECN-0101-2015-510-001220437