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자료유형
학술저널
저자정보
전수민 (조선대학교) 최문희 (조선대학교) 이용조 (조선대학교) 신현재 (조선대학교)
저널정보
한국생물공학회 KSBB Journal KSBB Journal 제28권 제6호
발행연도
2013.12
수록면
387 - 393 (7page)

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In this study, the domestic onion skin has been used to investigate the anti-wrinkle effect of the ethanolic extract. The onion skin has been known to contain a large amount of antioxidant including quercetin. Solvent extraction by 80% ethanol was carried out of the onion skin. The high amount of quercetin have been identified using HPLC as a bioactive compound. The extraction yield of the quercetin increased according to temperature up to 80℃. Two different antioxidant assays (DPPH and ABTS) were performed to determine the free-radical scavenging activity of onion skin extracts. The antioxidant activities (EC50 of DPPH) of the vitamin C and the onion extracts were 2.2 and 5.09 μg/mL, respectively. The results of ABTS tests were 2.33 (of vitamin C) and 2.40 μg/mL (of the onion extracts), respectively. In a clinical study, a panel of 10 female volunteers between the ages of 30 and 40 (mean age: 42 years) was given a mask pack containing 1% of this extracts for 4 weeks. It was shown that a highly significant reduction in the deep and moderate wrinkled was obtained with those treated with this onion extracts as compared to the control group. The reduction in deep wrinkles increased with time. Eye wrinkle were reduced statistically significant (p<0.05). The application of the proper topical cream and mask pack containing onion skin extracts has therefore shown to be effective enhancing anti-wrinkle activities.

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Abstract
1. 서론
2. 재료 및 방법
3. 결과 및 고찰
4. 결론
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UCI(KEPA) : I410-ECN-0101-2015-400-001299848