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학술대회자료
저자정보
조용상 (원광대학교) 홍명화 (가톨릭대학교) 김소연 (원광대학교) 이승재 (원광대학교) 이준희 (한국기계연구원) 김영율 (가톨릭대학교) 조영삼 (원광대학교)
저널정보
대한기계학회 대한기계학회 춘추학술대회 대한기계학회 2013년도 학술대회
발행연도
2013.12
수록면
3,822 - 3,825 (4page)

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In this study, a novel technique for dual-pore scaffold fabrication using SLUP (salt leaching using powder) and WNM (wire network molding) was proposed. To fabricated dual-pore scaffold, firstly, PCL with size of 63~100mm and NaCl powders with size of 100~180mm were prepared. Secondly, prepared PCL and NaCl powders were mixed using the stirrer at a certain ratio. Subsequently, stainless-steel needles with size of 500mm were inserted into a designed stainless steel mold. And then, the mixture powders were filled in the stainless-steel mold. Afterword, after the mold was pressurized at 30 MPa for 1 min using a lab-made compressor, the mold was heated to melt PCL powders in an oven at 100℃ for 20 min. Thereafter, after the stainless-steel needles were removed in the stainless-steel mold, the PCL/NaCl structure was separated from the stainless-steel mold. And then, the PCL/NaCl structure was soaked in D.I water for 24 hours using a sonicator to leach out the NaCl particles and dry for 24 hours in the desiccator. Consequently, the remaining PCL structure became the dual-pore scaffold. To analyze surface and cross-section characteristics of scaffolds, scaffolds was observed using SEM. Additionally, cell-culture experiments were performed using CCK-8 assay, ALP and compared with the bio-plotter and SLUP scaffolds.

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Abstract
1. Introduction
2. Material and Method
3. Result and discussion
4. Conclusion
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