It is known that 12-lead ECG has its limitations in the prediction of the ventricle posterior wall acute myocardial infarction(AMI). On the other hand, the 15-lead ECG consists of the 12-lead ECG with three additional leads. It’s detecting the posterior AMI of left ventricle. In this study we assessed the effectiveness of 15-lead ECG for the AMI tissue in ventricle posterior wall. To do this, we developed an electrophysiological model of the heart coupled with a torso model and the local AMI tissue model in posterior wall.