지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 111 - 118 (8page)
- DOI
- 10.14815/kjdm.2012.06.39.2.111
이용수
초록· 키워드
오류제보하기
Sand blast large grit acid etching (SLA) treated titanium (Ti) implant surfaces are known to enhance osteoblast activity. In this study, SLA treated Ti surface was modified by a low temperature RF discharge plasma with amine containing monomer such as allylamine (AAm), propylamine (PAAm) and evaluated in vitro cellular response. The change in wettability and surface morphology of pure Ti surface after the SLA treatment and plasma treatment were determined using contact angle measurement and field emission scanning electron microscopy. The chemical bonding state and chemical structure of amine plasma polymerized SLA/Ti surfaces were examined by Fourier transform infrared techniques and X-ray photoelectron spectroscopy. The surfaces of pure Ti, SLA treated Ti, and amine plasma polymerized SLA/Ti surfaces were also examined for their in vitro pre-osteoblast (MC3T3-E1) cells proliferation and differentiation using MTT assay and ALP activity test. The results of surface characterization showed that poly allylamine thin films was deposited on SLA/Ti surface after AAm and PAAm plasma treating for 15 min under a power of 30, 50, and 70W. The changes of surface chemistry and surface topography of Ti by AAm and PAAm plasma surface modification played main roles in improving the MC3T3-E1 cell proliferation and differentiation. These results suggest that amine containing polymeric thin films on the SLA treated Ti surface has an effect on proliferation and differentiation of MC3T3-E1 cells and potential use in osteo-conductive bone implants.
목차
ABSTRACT
서론
재료 및 방법
결과 및 고찰
결과
참고문헌
참고문헌 (14)
참고문헌 신청
1. [학술지(정기간행물)] - Adell R / 1990 / A long-term follow up study of osseointergratedimplants in the treatment of totally edentulosjaw / Int J Oral Maxillofac Implants 5 : 347 ~ 358
2. [학술지(정기간행물)] - Anderson JM / 1984 / Biomaterials biocompatibility and the macrophage / Biomaterial 5 : 5 ~ 10
3. [학술지(정기간행물)] - Barber TA / 2006 / In vitro characterization of peptide-modified p(AAm-co-EG/AAc) IPNcoated titaniumimplants / J Orthop Res 24 : 1366 ~ 1376
4. [학술지(정기간행물)] - Br nemark PI / 1969 / Intraosseous anchorage of dental protheses, I. Experimental studies / Scan J Plast Reconstr Surg 3 : 81 ~ 100
5. [학술지(정기간행물)] - Carsson L / 1998 / Removal torque for polished and rough titaniumimplant / Int J Oral Maxillofac Implants 3 : 21 ~ 24
2. [학술지(정기간행물)] - Anderson JM / 1984 / Biomaterials biocompatibility and the macrophage / Biomaterial 5 : 5 ~ 10
3. [학술지(정기간행물)] - Barber TA / 2006 / In vitro characterization of peptide-modified p(AAm-co-EG/AAc) IPNcoated titaniumimplants / J Orthop Res 24 : 1366 ~ 1376
4. [학술지(정기간행물)] - Br nemark PI / 1969 / Intraosseous anchorage of dental protheses, I. Experimental studies / Scan J Plast Reconstr Surg 3 : 81 ~ 100
5. [학술지(정기간행물)] - Carsson L / 1998 / Removal torque for polished and rough titaniumimplant / Int J Oral Maxillofac Implants 3 : 21 ~ 24
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UCI(KEPA) : I410-ECN-0101-2015-510-001117308