지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.6
- 수록면
- 147 - 152 (6page)
- DOI
- 10.14815/kjdm.2011.06.38.2.147
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초록· 키워드
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Titanium (Ti) have been widely used as biomaterials due to electrical and thermal conductivity and mechanical properties. To improve the biocompatibility, several surface treatment methods were suggested. Micro- and nano topography of Ti implant surface acts on major factor for osteoblast cell adhesion, proliferation and differentiation. In this study, we prepared nano- and micro structured TiO₂ surface and evaluated the biological activity of osteoblast like cell on the modified TiO₂ surface. TiO₂ surface of micro- and nano-mesh structured were prepared by SLA and alkaline treatment. Surface morphology and composition were characterized by FE-SEM (Field Emission scanning electron micrographs), and XRD (X-rat diffraction). To evaluate the MC3T3-E1 Cell proliferation and differentiation on modified TiO₂ surface, MTT assay and ALP activity were used. Alkaline treated Ti surface showed nano-mesh TiO₂ topographic characteristics. As the increase of immersing time in alkaline solution, nano-mesh size was gradually increased. SLA treated Ti surface showed good proliferation and differentiation of MC3T3-E1 cell compared to that of nano-mesh structured Ti surface.
목차
ABSTRACT
서론
재료 및 방법
결과 및 고찰
결과
참고문헌
참고문헌 (19)
참고문헌 신청
1. [단행본] - Adamson AW / 1997 / Physical Chemistry of Surfaces / Wiley
2. [학술지(정기간행물)] - Advincula MC / 2006 / Osteoblast adhesion and matrix mineralization on sol–gel derived titanium oxide / Biomaterials 27 : 2201 ~ 2212
3. [학술지(정기간행물)] - Albrektsson T / 1981 / Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone anchorage in man / Acta Orthop Scand 52 : 155 ~ 170
4. [학술지(정기간행물)] - Bachle M / 2004 / A systematic review of the influence of different titanium surfaces on proliferation, differentiation and protein synthesis of osteoblastlike MG63 cells / Clin Oral Implant Res 15 : 683 ~ 692
5. [학술지(정기간행물)] - Bagno A / 2004 / Surface treatments and roughness properties of Ti-based biomaterials / J Mater Sci Mat Med 15 : 935 ~ 949
2. [학술지(정기간행물)] - Advincula MC / 2006 / Osteoblast adhesion and matrix mineralization on sol–gel derived titanium oxide / Biomaterials 27 : 2201 ~ 2212
3. [학술지(정기간행물)] - Albrektsson T / 1981 / Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone anchorage in man / Acta Orthop Scand 52 : 155 ~ 170
4. [학술지(정기간행물)] - Bachle M / 2004 / A systematic review of the influence of different titanium surfaces on proliferation, differentiation and protein synthesis of osteoblastlike MG63 cells / Clin Oral Implant Res 15 : 683 ~ 692
5. [학술지(정기간행물)] - Bagno A / 2004 / Surface treatments and roughness properties of Ti-based biomaterials / J Mater Sci Mat Med 15 : 935 ~ 949
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UCI(KEPA) : I410-ECN-0101-2015-510-001123217