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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.12
- 수록면
- 263 - 272 (10page)
- DOI
- 10.14815/kjdm.2011.12.38.4.263
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초록· 키워드
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This study was performed to improve the bioactivity of anodized nanotubular TiO₂ layer. The glycerol solution containing 1 wt% NH4F and 20 wt% deionized water was used as an electrolyte. Pulse signals with a potential of 20 V and current density of 20 ㎃/㎠ were applied for 60 minutes. Nanotubular TiO₂ layer was heat-treated at 500℃ for 2 hours and precalcified by soaking in Na₂HPO₄ solution at room temperature for 24 hours and then in saturated Ca(OH)₂ solution for 5 hours. The samples were divided into 4 groups: (1) pure Ti; (2) anodized Ti; (3) anodized and heat-treated; and (4) anodized, heat-treated and precalcified. The 36 implants were placed in both tibiae of 18 rats. After implantation periods of 2 and 4 weeks, the degree of osseointegration of implants were evaluated by micro CT analysis, western blotting and RT-PCR. Micro CT images revealed more dense appearance around screw part of implants in the anodized, heat-treated, and precalcified group than in other groups. Bone mineral density and trabecular density values exhibited coherent results with same oder. Collagen Type I and 2 as well as osteocalcin which are involved in bone remodeling also exhibited the highest expression in the anodized, heat-treated, & precalcified group than in other groups. In conclusion, anodized, heat-treated, and precalcified titanium implants significantly improved osseointegration ability in compared to others.
목차
ABSTRACT
서론
재료 및 방법
결과
고찰
결론
참고문헌
참고문헌 (24)
참고문헌 신청
1. [학술지(정기간행물)] - Cheang P / 1996 / Addressing processing problems associated with plasma spraying or hydroxyapatite coatings / Biomaterials 17 : 537 ~ 544
2. [학술지(정기간행물)] - De Andrade MC / 2000 / Microstructure of ceramic coating on titanium surface as a result of hydrothermal treatment / J Mater Sci: Mater Med 11 : 751 ~ 755
3. [학술지(정기간행물)] - Elias CN / 2008 / Relationship between surface properties (roughness, wettability and morphology) of titanium and dental implant removal torque / J Mechanical Behavior of Biomaterials 1 : 234 ~ 242
4. [학술지(정기간행물)] - Fini M / 1999 / In vitro and in vivo behavior of Caand P-enriched anodized titanium / Biomaterials 20 : 1587 ~ 1594
5. [학술지(정기간행물)] - Hanawa T / 1996 / Microdissolution of calcium ions from calcium-ion-implanted titanium / Corros Sci 38 : 1579 ~ 1594
2. [학술지(정기간행물)] - De Andrade MC / 2000 / Microstructure of ceramic coating on titanium surface as a result of hydrothermal treatment / J Mater Sci: Mater Med 11 : 751 ~ 755
3. [학술지(정기간행물)] - Elias CN / 2008 / Relationship between surface properties (roughness, wettability and morphology) of titanium and dental implant removal torque / J Mechanical Behavior of Biomaterials 1 : 234 ~ 242
4. [학술지(정기간행물)] - Fini M / 1999 / In vitro and in vivo behavior of Caand P-enriched anodized titanium / Biomaterials 20 : 1587 ~ 1594
5. [학술지(정기간행물)] - Hanawa T / 1996 / Microdissolution of calcium ions from calcium-ion-implanted titanium / Corros Sci 38 : 1579 ~ 1594
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