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논문 기본 정보

자료유형
학술저널
저자정보
Dong Sik Bae (Inje University College of Medicine) Jung-Woo Woo (Seoul National University Hospital) Se Hyun Paek (Seoul National University Hospital) Hyungju Kwon (Seoul National University Bundang Hospital) Young Jun Chai (Seoul National University Hospital) Su-jin Kim (Seoul National University Hospital) June Young Choi (Seoul National University Bundang Hospital) Kyu Eun Lee (Seoul National University Hospital) Yeo-Kyu Youn (Seoul National University Hospital)
저널정보
대한외과학회 Annals of Surgical Treatment and Research Journal of the Korean Surgical Society Vol.85 No.5
발행연도
2013.11
수록면
199 - 204 (6page)

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초록· 키워드

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Purpose: A number of researchers have suggested the use of sodium hyaluronate carboxymethyl cellulose (HA-CMC) membrane for preventing postoperative adhesion. This study evaluated the antiadhesive effect and safety of HA-CMC membrane in thyroidectomy for papillary thyroid cancer.
Methods: One hundred sixty-two patients who underwent thyroidectomy were prospectively randomized. In the study group of 80 patients, the 7.5 cm × 13 cm HA-CMC membrane was applied to the operative field after thyroidectomy. The subjects were asked about complications including adhesive symptoms using an 8-item questionnaire at 2 weeks, 3 months, and 6 months after surgery. In addition,
items on the appearance of neck wrinkles and scars were evaluated by a physician who had no information about the patient’s allocation.
Results: There were no significant differences in complications such as swallowing difficulty, and wrinkles between study and control groups. Both groups presented significantly decreased scores over time in swallowing difficulty, and wrinkles. There were no complications regarding the HA-CMC membrane.
Conclusion: The antiadhesive effect of HA-CMC membrane in thyroid surgery is still uncertain, although it is biologically safe. Further investigation is needed to confirm the antiadhesive effect of HA-CMC membrane in thyroid surgery.

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INTRODUCTION
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