지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: The purpose of this study was to investigate the effects of Zeae Stigma herbal-acupuncture (ZS-HA) at KI10 (Umgok) on nephritis induced by lipopolysaccharide (LPS) in rats.
Methods: Rats were assigned to five groups, normal, LPS, NP, saline and ZS-HA. Rats in NP, saline, and ZS-HA groups were treated with needle prick, saline injection, and ZS-HA respectively at KI10, three times a week. All animals except the normal group were injected intra-peritoneally with LPS to induce nephritis. RBC and WBC, neutrophils in blood, TNF-alpha, CINC-1, creatinine in serum, urinal volume, total protein and creatinine in urine, and renal MPO were analyzed.
Results: Needle prick at KI10 significantly reduced WBC in blood and CINC-1 in serum of LPS-stimulated rats. Saline injection at KI10 significantly reduced TNF-α in serum and total protein in urine of LPS-stimulated rats. ZS-HA at KI10 significantly increased RBC in blood, and significantly reduced neutrophils in blood, TNF-α in serum, and total protein in urine of LPS-stimulated rats.
Conclusions: According to these results, it is postulated that ZS-HA at KI10 has anti-inflammatory and renal-protective effects on LPS-induced nephritis in rats, and both acupoint KI10 and herb Zeae Stigma made contributions to this effect. Further studies on the interaction between acupoint KI10 and herb Zeae Stigma may be needed.
Methods: Rats were assigned to five groups, normal, LPS, NP, saline and ZS-HA. Rats in NP, saline, and ZS-HA groups were treated with needle prick, saline injection, and ZS-HA respectively at KI10, three times a week. All animals except the normal group were injected intra-peritoneally with LPS to induce nephritis. RBC and WBC, neutrophils in blood, TNF-alpha, CINC-1, creatinine in serum, urinal volume, total protein and creatinine in urine, and renal MPO were analyzed.
Results: Needle prick at KI10 significantly reduced WBC in blood and CINC-1 in serum of LPS-stimulated rats. Saline injection at KI10 significantly reduced TNF-α in serum and total protein in urine of LPS-stimulated rats. ZS-HA at KI10 significantly increased RBC in blood, and significantly reduced neutrophils in blood, TNF-α in serum, and total protein in urine of LPS-stimulated rats.
Conclusions: According to these results, it is postulated that ZS-HA at KI10 has anti-inflammatory and renal-protective effects on LPS-induced nephritis in rats, and both acupoint KI10 and herb Zeae Stigma made contributions to this effect. Further studies on the interaction between acupoint KI10 and herb Zeae Stigma may be needed.
목차
서론
실험
성적
고찰
참고문헌
참고문헌 (27)
참고문헌 신청
1. [단행본] - Du HK / 1993 / Oriental Kidney System Internal Medicine / Oriental Science Research Association : 226 ~ 336
2. [단행본] - Lee WJ / 2000 / Medical Dictionary / Academy Press : 724 ~
3. [단행본] - J. CLAUDE bennett / 1996 / Cecil textbookof medicine. 20th / saunders : 552 ~ 577
4. [인터넷자원] - / / Frequent 22 Disease Classification Payroll Status. 2004-2011
5. [인터넷자원] - / / Acute Glomerulonephritis. 2005
2. [단행본] - Lee WJ / 2000 / Medical Dictionary / Academy Press : 724 ~
3. [단행본] - J. CLAUDE bennett / 1996 / Cecil textbookof medicine. 20th / saunders : 552 ~ 577
4. [인터넷자원] - / / Frequent 22 Disease Classification Payroll Status. 2004-2011
5. [인터넷자원] - / / Acute Glomerulonephritis. 2005
이 논문의 저자 정보
최근 본 자료
댓글(0)
0