지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.10
- 수록면
- 435 - 441 (7page)
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초록· 키워드
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This study investigated the effects of Korean Red Ginseng (KRG) on radiation-induced bone loss in C3H/HeN mice. C3H/HeN mice were divided into sham and irradiation (3 Gy, gamma-ray) groups. The irradiated mice were treated for 12 wk with vehicle, KRG (per os, p.o.) or KRG (intraperitoneal). Serum alkaline phosphatase (ALP), tartrate-resistant acid phosphatase, estradiol level, and biomechanical properties were measured. Tibiae were analyzed using micro-computed tomography. Treatment of KRG (p.o., 250 mg/kg of body weight/d) significantly preserved trabecular bone volume, trabecular number, structure model index, and bone mineral density of proximal tibia metaphysic, but did not alter the uterus weight of the mice. Serum ALP level was slightly reduced by KRG treatment. However, grip strength, mechanical property, and cortical bone architecture did not differ among the experimental groups. The results indicate that KRG can prevent radiation-induced bone loss in mice.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Howland WJ / 1975 / Postirradiation atrophic changes of bone and related complications / Radiology 117 : 677 ~ 685
2. [학술지(정기간행물)] - Ergun H / 1980 / Postradiation atrophy of mature bone / CRC Crit Rev Diagn Imaging 12 : 225 ~ 243
3. [학술지(정기간행물)] - Chen HH / 2002 / Changes in bone mineral density of lumbar spine after pelvic radiotherapy / Radiother Oncol 62 : 239 ~ 242
4. [학술지(정기간행물)] - Liu Z / 2002 / The diagnostic criteria for primary osteoporosis and the incidence of osteoporosis in China / J Bone Miner Metab 20 : 181 ~ 189
5. [학술지(정기간행물)] - Harada S / 2003 / Control of osteoblast function and regulation of bone mass / Nature 423 : 349 ~ 355
2. [학술지(정기간행물)] - Ergun H / 1980 / Postradiation atrophy of mature bone / CRC Crit Rev Diagn Imaging 12 : 225 ~ 243
3. [학술지(정기간행물)] - Chen HH / 2002 / Changes in bone mineral density of lumbar spine after pelvic radiotherapy / Radiother Oncol 62 : 239 ~ 242
4. [학술지(정기간행물)] - Liu Z / 2002 / The diagnostic criteria for primary osteoporosis and the incidence of osteoporosis in China / J Bone Miner Metab 20 : 181 ~ 189
5. [학술지(정기간행물)] - Harada S / 2003 / Control of osteoblast function and regulation of bone mass / Nature 423 : 349 ~ 355
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UCI(KEPA) : I410-ECN-0101-2014-520-002777926